A new method for studying the effect of pH on the polysiloxane network formation using electric fields is presented. The kinetic data obtained using these experiments indicates that the two-step interfacial polycondensation of silanes is strongly dependent on the pH, and the mechanism is essentially different at low and neutral to high values of pH. Very rapid hydrolysis followed by moderate rates of condensation are observed at neutral and high pH. The rate of hydrolysis is drastically reduced, while that of condensation is slightly lowered at low pH as compared to that at high values of pH. The slow hydrolysis reaction at low pH is then exploited to synthesize nonspherical microcapsules. Nonspherical polysiloxane microcapsules with varying aspect ratios from 1.05to 1.97 are synthesized by controlling the applied electric field.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/la501617t | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Oxidative Stability of Fish Oil-Loaded Nanocapsules Produced by Electrospraying Using Kafirin or Zein Proteins as Wall Materials.
Antioxidants (Basel)
September 2024
Department of Chemical Engineering, University of Granada, 18071 Granada, Spain.
The encapsulation of fish oil by monoaxial electrospraying using kafirin or zein proteins as hydrophobic wall materials was investigated. Kafirin resulted in spherical fish oil-loaded nanocapsules (>50% of capsules below 1 µm), whereas zein led to fish oil-loaded nanocapsules with non-spherical morphology (>80% of capsules below 1 µm). Both hydrophobic encapsulating materials interacted with fish oil, successfully entrapping the oil within the protein matrix as indicated by Fourier-transform infrared spectroscopy (FTIR) and Raman spectroscopy results.
View Article and Find Full Text PDFIonic Polymerization-Based Synthesis of Bioinspired Adhesive Hydrogel Microparticles with Tunable Morphologies from Microfluidics.
ACS Appl Mater Interfaces
July 2024
The State Key Laboratory of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, P. R. China.
Shape-anisotropic hydrogel microparticles have attracted considerable attention for drug-delivery applications. Particularly, nonspherical hydrogel microcarriers with enhanced adhesive and circulatory abilities have demonstrated value in gastrointestinal drug administration. Herein, inspired by the structures of natural suckers, we demonstrate an ionic polymerization-based production of calcium (Ca)-alginate microparticles with tunable shapes from Janus emulsion for the first time.
View Article and Find Full Text PDFRecent Progress of Droplet Microfluidic Emulsification Based Synthesis of Functional Microparticles.
Glob Chall
September 2023
The remarkable control function over the functional material formation process enabled by droplet microfluidic emulsification approaches can lead to the efficient and one-step encapsulation of active substances in microparticles, with the microparticle characteristics well regulated. In comparison to the conventional fabrication methods, droplet microfluidic technology can not only construct microparticles with various shapes, but also provide excellent templates, which enrich and expand the application fields of microparticles. For instance, intersection with disciplines in pharmacy, life sciences, and others, modifying the structure of microspheres and appending functional materials can be completed in the preparation of microparticles.
View Article and Find Full Text PDFDomes and semi-capsules as model systems for infrared microspectroscopy of biological cells.
Sci Rep
February 2023
Faculty of Science and Technology, Norwegian University of Life Sciences, 1430, Aas, Norway.
It is well known that infrared microscopy of micrometer sized samples suffers from strong scattering distortions, attributed to Mie scattering. The state-of-the-art preprocessing technique for modelling and removing Mie scattering features from infrared absorbance spectra of biological samples is built on a meta model for perfect spheres. However, non-spherical cell shapes are the norm rather than the exception, and it is therefore highly relevant to evaluate the validity of this preprocessing technique for deformed spherical systems.
View Article and Find Full Text PDFRecent progress in the synthesis of all-aqueous two-phase droplets using microfluidic approaches.
Colloids Surf B Biointerfaces
November 2022
Department of Chemical Engineering and Applied Chemistry, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea. Electronic address:
Article Synopsis
- An aqueous two-phase system (ATPS) is a liquid-liquid phase separation method beneficial for extracting and purifying various biomolecules, providing a biocompatible and environmentally friendly alternative to traditional emulsion systems.
- While ATPS holds potential in biomedicine, generating stable water-in-water (w-in-w) emulsion droplets is challenging due to their ultra-low interfacial tension, with existing techniques like bulk emulsification resulting in a mixture of droplet sizes.
- Microfluidic platforms offer a promising solution by producing uniform, spherical w-in-w droplets efficiently, allowing for better control in the fabrication of microparticles and microcapsules, and showcasing significant advancements in ATPS emulsions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!