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Clinical significance criteria in the ICSD and DSM sleep disorder classifications: a content overlap analysis using the Jaccard index.
J Clin Sleep Med
January 2025
Univ. Bordeaux, CNRS, SANPSY, UMR 6033, F-33000 Bordeaux, France.
Study Objectives: Both the (ICSD) and the sleep-wake disorders section of the (DSM) emphasize the importance of clinical judgment in distinguishing the normal from the pathological in sleep medicine. The fourth edition of the DSM (DSM-IV, 1994) introduced the clinical significance criterion (CSC) to standardize this judgment and enhance diagnostic reliability.
Methods: This review conducts a theoretical and historical content analysis of CSC presence, frequency, and formulation in the diagnostic criteria of sleep disorders.
Development of Research Foundation for Comprehensive Articulation of Drug Effects.
Biol Pharm Bull
January 2025
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
As unexpected adverse events and successful drug repositioning have shown, drug effects are complex and include aspects not recognized by developers. How can we understand these unrecognized drug effects? Drug effects can be numerized by encompassing biological responses to drugs. For instance, the transcriptome data of cultured cells and toxicopathological images of mice treated with a compound represent the effects of the compound in vitro and in vivo, respectively.
View Article and Find Full Text PDFTime-series InSAR measurement using ICOPS and estimation of along-track surface deformation using MAI during the 2021 eruption of Fagradalsfjall Volcano, Iceland.
Sci Rep
December 2024
Department of Science Education, Kangwon National University, 1 Gangwondaehak-gil, Chuncheon-si, 24341, Gangwon-do, Republic of Korea.
The eruption in Fagradalsfjall Volcano, located in Reykjanes Peninsula, Iceland, from several centuries' dormant states, occurred for the first time on March 19, 2021. Observations of Fagradalsfjall Volcano were conducted in 2021, and the eruption period lasted for six months until 18 September 2021. Six days pair of interferograms were generated from ninety synthetic aperture radar (SAR) data.
View Article and Find Full Text PDFUnderstanding Healthcare Barriers for Latino/a/e/x Families with Alzheimer's Disease: Insights from Primary Care Provider interviews.
medRxiv
December 2024
University of Kansas Alzheimer's Disease Center, School of Medicine, University of Kansas Medical Center, Fairway, KS, USA.
Background: Alzheimer's Disease and Related dementias (ADRD) are disproportionately underdiagnosed, misdiagnosed, and undertreated in Latino/a/e/x populations living in the U.S. Latino/a/e/x families also experience low access to ADRD caregiver support services and high levels of depression.
View Article and Find Full Text PDFQuality of vision with monofocal intraocular lens after cataract surgery: Comprehensive evaluation and graphical illustration.
Eur J Ophthalmol
December 2024
Ophthalmology Unit, Centro Hospitalar Universitário de Coimbra (CHUC), Unidade Local de Saúde (ULS) de Coimbra, Coimbra, Portugal.
Article Synopsis
- The study aimed to assess the quality of vision (QV) in patients undergoing bilateral cataract surgery with a specific type of intraocular lens (IOL) in Portugal, and it proposes a graphical representation for clarity.
- A total of 26 patients, averaging 68 years old, were evaluated three months post-surgery on various visual performance metrics, including uncorrected and corrected visual acuity, reading speed, contrast sensitivity, and more.
- Results indicated high patient satisfaction correlated with multiple factors, and the study successfully created a radar graph to visualize the comprehensive data on visual performance.
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