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Biochemical and immunological properties of the human carcinoma antigen CAR-5 defined by the monoclonal antibody BD-5.
Int J Cancer
July 1989
Department of Biomedical Sciences and Oncology, School of Medicine, University of Turin, Italy.
The monoclonal antibody (MAb) BD-5 reacts with an epitope (CAR-5) expressed in 83% of the gastric carcinomas and in 51% of the ductal pancreatic carcinomas. This MAb reacts also with epithelial cells of colorectal mucosa, but does not react at all with normal adult gastric mucosa or normal adult pancreas. We report the biochemical and immunochemical characterization of CAR-5-bearing molecule.
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