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A Clinic-Level Approach to Improve Uptake of First COVID-19 Vaccine Dose in Primary Care.
J Health Care Poor Underserved
November 2024
This quality improvement initiative aimed to increase first dose of COVID-19 vaccinations during pediatric/adolescent clinic visits. Four plan-do-study-act cycles were performed with creation of eligibility lists and increasing health educator (HE) engagement. Statistical process control analysis assessed vaccine receipt over time.
View Article and Find Full Text PDFPhenotypic spectrum and tumor risk in Simpson-Golabi-Behmel syndrome: Case series and comprehensive literature review.
Am J Med Genet A
December 2024
Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Simpson-Golabi-Behmel syndrome (SGBS) is a rare congenital overgrowth condition characterized by macrosomia, macroglossia, coarse facial features, and development delays. It is caused by pathogenic variants in the GPC3 gene on chromosome Xq26.2.
View Article and Find Full Text PDFAn expert panel on the adequacy of safety data and physiological roles of dietary bovine osteopontin in infancy.
Front Nutr
June 2024
Nutrispectives, LLC, Spokane, WA, United States.
Human milk, due to its unique composition, is the optimal standard for infant nutrition. Osteopontin (OPN) is abundant in human milk but not bovine milk. The addition of bovine milk osteopontin (bmOPN) to formula may replicate OPN's concentration and function in human milk.
View Article and Find Full Text PDFDiagnostic markers of acute encephalitis syndrome and COVID-associated multisystem inflammatory syndrome in children from Southern India.
J Med Virol
May 2024
Department of Neurovirology, National Institute of Mental Health & Neurosciences, Bangalore, India.
Article Synopsis
- Acute encephalitis syndrome (AES) in children is a major health issue in India, and this study evaluates the role of inflammatory mediators and neurofilament (NfL) levels in differentiating the causes, understanding disease severity, and predicting outcomes in AES.* -
- The research analyzed serum and cerebrospinal fluid (CSF) samples from 62 children with AES, finding that markers differed significantly among scrub typhus, viral infections, and COVID-related multisystem inflammatory syndrome (MIS-C), with specific levels of cytokines revealing patterns that aid in diagnosis.* -
- The study concluded that certain serum markers could effectively differentiate between scrub typhus and other types of AES, and higher levels of certain
Diagnosis and Management of Macrosomia and Shoulder Dystocia: A Comprehensive Review of Major Guidelines.
Obstet Gynecol Surv
April 2024
Assistant Professor.
Importance: Macrosomia represents the most significant risk factor of shoulder dystocia (SD), which is a severe and emergent complication of vaginal delivery. They are both associated with adverse pregnancy outcomes.
Objective: The aim of this study was to review and compare the most recently published influential guidelines on the diagnosis and management of fetal macrosomia and SD.
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