Ischemic stroke is a recognized complication of herpes zoster ophthalmicus. Arterial involvement is usually seen on the side of the rash. It is thought to be due to vessel inflammation by the virus, which travels from the trigeminal ganglion. Few case reports of bilateral and distant site of zoster lesions with stroke in the brain have been described. These reports suggest possibility of contiguous vascular, cerebrospinal fluid (CSF) or hematogenous spread of the virus from the ganglion to the cerebral blood vessels. Therapeutically acyclovir, anticoagulation, and steroids have been used in the treatment of the zoster associated with stroke. We describe a case of immunocompromised patient with ipsilateral zoster ophthalmicus with bilateral anterior circulation strokes, who was treated with above measures and made successful recovery. This report also raises/supports possible CSF/vascular/hematogenous spread of the virus from the ganglion to involve cerebral blood vessels leading to the stroke.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078612 | PMC |
| http://dx.doi.org/10.4103/0976-3147.133584 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report.
BMC Ophthalmol
January 2025
Isfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Herpes zoster Ophthalmicus (HZO) affecting the ophthalmic division (V1) of the trigeminal nerve. HZO may cause extraocular muscle palsies, with the third nerve being the most commonly affected and the fourth nerve the least. The combined involvement of the optic nerve and isolated paralysis of the eye muscle is very rare, with only limited case reports documenting this complication of ocular herpes zoster.
View Article and Find Full Text PDFHerpes zoster ophthalmicus temporally after COVID-19 vaccination: a systematic review of uncontrolled case reports and case series.
Proc (Bayl Univ Med Cent)
December 2024
College of Medicine, Texas A&M University, Houston, Texas, USA.
Purpose: Herpes zoster ophthalmicus (HZO) following COVID-19 vaccination has been reported previously but the clinical characteristics, onset, treatment, and outcomes of these cases have not been previously systematically reviewed.
Methods: A systematic review, guided by PRISMA guidelines, surveyed PubMed and Embase databases from April 2021 to June 2023 for case reports and series detailing HZO following COVID-19 vaccination. Studies excluded were abstracts, reviews, and clinical trials.
Management of Herpes Zoster Ophthalmicus with Optic Neuritis and Cavernous Sinus Involvement: A Case Report.
Ocul Immunol Inflamm
December 2024
Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA.
Purpose: To report a treatment approach of a rare presentation of herpes zoster ophthalmicus (HZO) with optic neuropathy and oculomotor nerve palsy.
Methods: Report of one case.
Results: Multiple lesions involving the optic nerve and cavernous sinus were demonstrated on magnetic resonance imaging in a patient with a characteristic herpes zoster rash in the V1 dermatomal distribution.
Tear inflammatory cytokine profiles in orbital inflammatory disease.
Exp Eye Res
December 2024
Department of Ophthalmology, The Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Tear inflammatory cytokines are a novel biomarker studied in a range of ocular surface diseases, periorbital and orbital conditions. This single-centre prospective study between 2022 and 2024 aims to characterise tear cytokine profiles (Interleukin-1β [IL-1β], IL-2, IL-6, Interferon-γ [IFN-γ] and Tumour Necrosis Factor-α [TNF- α]) in orbital inflammatory disease (OID). OID patients had pre-treatment tear collection via micropipette, and cytokine analysis via multiplex bead array analysis.
View Article and Find Full Text PDFTrigeminal nerve imaging abnormalities in a child with herpes zoster ophthalmicus.
Pediatr Radiol
December 2024
Imperial College Healthcare NHS Trust, London, UK.
Article Synopsis
- Reactivation of the latent varicella zoster virus in the trigeminal ganglion can lead to herpes zoster ophthalmicus, which is uncommon in children and usually diagnosed clinically without imaging.
- Recent studies on imaging abnormalities associated with this condition in children are limited.
- A new case report presents a healthy child with herpes zoster ophthalmicus who showed enlargement and enhancement of the trigeminal nerve and its branches on MRI, highlighting a potential imaging feature that hasn't been documented before in pediatric cases.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!