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Bisphenol A and its potential mechanism of action for reproductive toxicity.
Toxicology
December 2024
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Canada; School of Environmental Studies, Queen's University, Kingston, Canada. Electronic address:
Bisphenol A (BPA) is an organic synthetic chemical used worldwide. Billions of pounds of BPA are produced annually through industrial processes to be used in commercial products, making human exposure to BPA ubiquitous. Concerns have been raised due to the potential adverse health effects of BPA, specifically in vulnerable populations, such as pregnant persons and children.
View Article and Find Full Text PDF[Construction of a 17-estradiol sensor based on a magnetic graphene oxide/aptamer separating material].
Se Pu
January 2025
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
17-Estradiol (E2) is a natural steroidal estrogen essential for a variety of physiological functions in organisms. However, external E2, which is renowned for its potent biological effects, is also considered to be an endocrine-disrupting compound (EDC) capable of disturbing the normal operation of the endocrine system, even at nanogram-per-liter (ng/L) concentrations. Studies have revealed that medical and livestock wastewater can be contaminated with E2, which poses potential risks to human health.
View Article and Find Full Text PDFPhotocatalytic Estrogen Degradation by the Composite of Tin Oxide Fine Particles and Graphene-like Carbon Nitride.
ACS Omega
December 2024
Department of Life Science and Applied Chemistry, Nagoya Institute of Technology Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
This study investigates whether 17β-estradiol (E2), a natural estrogen and one of the endocrine-disrupting chemicals responsible for water pollution, can be oxidatively decomposed under simulated solar light using a composite of tin oxide nanoparticles and graphene-like carbon nitride (g-CN) as a photocatalyst. The composite photocatalyst was prepared by heating a mixture of urea and tin acetate. FT-IR measurements revealed that g-CN possesses structural units similar to g-CN, a well-studied graphite-like carbon nitride.
View Article and Find Full Text PDFComparative effectiveness of vitrification and slow freezing after heterotopic transplantation of human ovarian tissues.
BMC Womens Health
December 2024
Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Background: The aim of this study was to compare the effectiveness of two different vitrification methods and slow freezing in terms of the recovery of endocrine function, follicular morphology and proliferation, apoptosis of stromal cells, and angiogenesis after heterotopic transplantation of human ovarian tissue.
Methods: Ovarian tissue from young women aged 29 to 40 was subjected to two vitrification methods and one slow freezing method. The thawed ovarian tissue was then transplanted into nude mice and divided into three groups (VF1 group, VF2 group, SF group) according to the different freezing methods.
Infant mice fed soy-based formulas exhibit alterations in anxiety-like behaviours and the 5-HT system.
Toxicology
December 2024
Neuroscience Institute Cavalieri Ottolenghi (NICO), Regione Gonzole 10, Orbassano, Torino 10043, Italy; Department of Neuroscience 'Rita Levi Montalcini', University of Torino, Via Cherasco 15, Torino 10126, Italy. Electronic address:
Genistein (GEN) is a phytoestrogen with oestrogen-like activity found in many plants. Classified as an endocrine disruptor, GEN is potentially hazardous, particularly during developmental stages. It induces alterations in anxious behaviour, fertility, and energy metabolism, alongside modifications in specific brain circuits.
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