Objective: To determine whether hysterosalpingo-foam sonography (HyFoSy) is a less painful first line tubal patency test than serial hysterosalpingography (HSG).
Design: A two-center, prospective, open-label, randomized, controlled trial.
Setting: University hospital and teaching hospital.
Patient(s): 40 subfertile women, ages 18 to 41 years, with an indication for tubal patency testing as part of the fertility workup according to the Dutch Nederlandse Vereniging voor Obsteterie & Gynaecologie-guidelines.
Intervention(s): Tubal patency testing by HyFoSy versus serial HSG.
Main Outcome Measure(s): Visual Analogue Scale (VAS) pain scores during tubal patency testing.
Result(s): The median VAS score for pain perception during the HyFoSy procedure was 1.7 cm (interquartile range: 2.1) compared with 3.7 cm (interquartile range: 4.2) during HSG. The HyFoSy procedure also had a statistically significantly shorter procedure time compared with HSG, with a median of 5.0 minutes (interquartile range: 3.0) for HyFoSy versus 12.5 minutes (interquartile range: 16.0) for HSG.
Conclusion(s): The HyFoSy procedure is a less painful and less time-consuming tubal patency test compared with HSG.
Clinical Trial Registration Number: Netherlands National Trial Register NTR3457.
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| http://dx.doi.org/10.1016/j.fertnstert.2014.05.042 | DOI Listing |
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