Cytochrome P-450 forms appearing in the liver after injection of methylcholanthrene, polychlorinated biphenyls and perfluorochemical emulsion to rats were studied. Activities of marker enzymes, benzpyrenehydroxylase and 7-ethoxyresorufin-O-deethylase, as well as the interaction of liver microsomal membranes with antibodies against different cytochrome forms were investigated. It was shown that fluorocarbon emulsion containing perfluorodecalin did not induce cytochrome P-448 in the rat liver.

Download full-text PDF

Source

Publication Analysis

Top Keywords

induce cytochrome
8
cytochrome p-448
8
p-448 rat
8
[perfluorocarbons induce
4
cytochrome
4
rat liver]
4
liver] cytochrome
4
cytochrome p-450
4
p-450 forms
4
forms appearing
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!