AI Article Synopsis
- Spiroindolenine derivatives are created using a reaction that involves a palladium catalyst and indoles.
- This process involves the interaction of indoles with propargyl carbonate in a step-by-step manner.
- The method results in the formation of spiroindolenines or spiroindolines with high efficiency, yielding good to excellent amounts of product.
Article Abstract
Spiroindolenine derivatives were synthesized by intermolecular Pd-catalyzed dearomatization of indoles. The reaction between nucleophile bearing indoles and propargyl carbonate proceeds in a cascade fashion providing spiroindolenines or spiroindolines in good to excellent yields.
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| http://dx.doi.org/10.1021/ol501704q | DOI Listing |
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