Advances in biomathematical modeling for PET neuroreceptor imaging.

Drug Discov Today Technol

Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, London, Du Cane Road, W12 0NN, UK.

Published: July 2014

The quantitative application of PET neuroreceptor imaging to study pathophysiology, diagnostics and drug development has continued to benefit from associated advances in biomathematical imaging methodology. We review some of these advances with particular focus on multi-modal image processing, tracer kinetic modeling, occupancy studies and discovery and development of novel radioligands.:

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http://dx.doi.org/10.1016/j.ddtec.2012.01.001DOI Listing

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