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Viability assessment of Chlamydia trachomatis in men who have sex with men using molecular and culture methods.
Clin Microbiol Infect
January 2025
Chlamydia Group, Institute of Veterinary Pathology; University of Zürich, Switzerland.
Objectives: Chlamydia trachomatis is the most commonly diagnosed bacterial sexually transmitted infection (STI) worldwide. Diagnosis relies on nucleic acid amplification techniques, such as PCR, which does not distinguish between viable pathogens and residual bacterial DNA, leading to potential overdiagnosis and overtreatment. PCR with confirmation of pathogen viability has not been widely explored in the STI field.
View Article and Find Full Text PDFNegotiating Normalcy: Epistemic Errors in Self-Diagnosing Late-ADHD.
Cult Med Psychiatry
January 2025
Roskilde University, Universitetsvej 1, 4000, Roskilde, Denmark.
In this paper, I share insights from ongoing ethnographic fieldwork among adult Danes who identify as having Attention Deficit Hyperactivity Disorder (ADHD) but do not meet the clinical standards and have yet to receive a diagnosis. These individuals are particularly relevant to the ongoing debates about under- and overdiagnosis of ADHD, as their claims to the diagnosis influence and mirror societal perceptions of what is considered normal and what is seen as a condition. Despite their symptoms not strictly meeting diagnostic criteria, thus risking overdiagnosis and associated psychiatric labeling, they perceive themselves as distinct from 'normal' people.
View Article and Find Full Text PDFPI-RADS 3 MRI lesions: Are biopsies still necessary?
Fr J Urol
January 2025
Department of Urology, North Hospital, AP-HM, Marseille, France.
Introduction: A significant proportion of newly diagnosed prostate cancer (PCa) cases are slow growing with a low risk of metastatic progression. There is a lack of data concerning the optimal biopsy regimen for improving diagnosis yield in PI-RADS3 lesions. This study aimed to assess the diagnostic value of current biopsy regimens in PI-RADS 3 lesions and identify clinical predictors to improve clinically significant PCa (csPCa) detection.
View Article and Find Full Text PDFThe ADHD Assessment Quality Assurance Standard for Children and Teenagers (CAAQAS).
Neuropsychiatr Dis Treat
December 2024
Fulbourn Hospital, Cambridgeshire and Peterborough Foundation NHS Trust, Cambridge, UK.
Around 5% of the children and teenagers worldwide are affected by Attention-Deficit/Hyperactivity Disorder [ADHD], making it a major public health concern. Recently, demand for assessments has substantially increased, putting strain on healthcare and waiting lists. There is concern that pressure to clear service bottlenecks is leading to variable quality and reliability of ADHD assessments in this population.
View Article and Find Full Text PDFBackground: Artificial intelligence (AI) has significantly impacted medical imaging, particularly in gastrointestinal endoscopy. Computer-aided detection and diagnosis systems (CADe and CADx) are thought to enhance the quality of colonoscopy procedures.
Summary: Colonoscopy is essential for colorectal cancer screening, but often misses a significant percentage of adenomas.
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