While initial phylogenetic analyses concluded to Guinea 2014 EBOV falling outside the Zaïre lineage (ZEBOV), a recent re-analysis of the same dataset by Dudas and Rambaut (2014) suggested that Guinea 2014 EBOV actually is ZEBOV. Under the same hypothesis as used by these authors (the molecular clock hypothesis), we reinforce their conclusion by providing a statistical assessment of the location of the root of the Zaïre lineage. Our analysis unambiguously supports Guinea 2014 EBOV as a member of the Zaïre lineage. In addition, we also show that some uncertainty exists so as to the location of the root of the genus Ebolavirus. We release the software we used for these re-analyses. RootAnnotator allows for the easy determination of branch root posterior probability from any posterior sample of clocked trees and is freely available at http://sourceforge.net/projects/rootannotator/.
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http://dx.doi.org/10.1371/currents.outbreaks.c0e035c86d721668a6ad7353f7f6fe86 | DOI Listing |
Trop Med Infect Dis
November 2024
Centre National de Formation et de Recherche en Santé Rurale de Mafèrinyah, Forécariah GPW7+V9G, Guinea.
This study analyzed the trend and factors associated with medical-surgical complications in patients discharged from leprosy multidrug therapy at the Centre Hospitalier Régional Spécialisé (CHRS), in Macenta, Republic of Guinea. This was a retro 2012 ( = 54) and 2013 ( = 35) and then a slight decrease between 2014 ( = 34) and 2017 ( = 26). From 2019 ( = 18) to 2021 ( = 1), a significant d spective study using routine secondary data from 2012 to 2021.
View Article and Find Full Text PDFHealth Promot Pract
November 2024
Office of Readiness and Response, Centers for Disease Control and Prevention, Atlanta, GA, USA.
The first Ebola Virus Disease (EVD) cases in the 2021 Ebola outbreak were reported by the Democratic Republic of the Congo (DRC) Ministry of Health in February. However, 1 week later, the Guinea Ministry of Health reported its first EVD outbreak since April 2016. U.
View Article and Find Full Text PDFNat Immunol
December 2024
Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA.
Math Biosci
December 2024
School of Computer Science and Applied Mathematics, University of the Witwatersrand, Johannesburg, South Africa. Electronic address:
We construct a new metapopulation model for the transmission dynamics and control of the Ebola Virus Disease (EVD) in an environment characterized by considerable migrations and travels of people. It is an extended SEIR model modified by the addition of Quarantine and Isolated compartments to account for travelers who undergo the exit screening. The model is well-fitted by using the reported cases from the neighboring countries Guinea, Liberia and Sierra Leone where the 2014-2016 Ebola outbreak simultaneously arose.
View Article and Find Full Text PDFSci Total Environ
December 2024
Department of Water Resources Management and Agrometeorology, Federal University, PMB 373, Oye, Ekiti 371104, Nigeria.
Soil erosion is a critical environmental challenge with significant implications for agriculture, water quality, and ecosystem stability. Understanding its dynamics is essential for sustainable environmental management and societal welfare. Here, we analyze rainfall erosivity and erosion patterns across West Africa (WAF) during the historical (1982-2014), near future (2028-2060), and far future (2068-2100) periods under Shared Socioeconomic Pathways (SSPs 370 and 585).
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