This study chose zero-inflated model and Hurdle model that have been widely used in economic and social fields to model the fire occurrence in Tahe, Daxing'an Mountain. The AIC, LR and SSR were used to compare the models including zero-inflated Poisson model (ZIP), zero-inflated negative binomial model (ZINB), Poisson-Hurdle model (PH) and negative Binomial Hurdle (NBH) (two types, four models in total) so as to determine a better-fit model to predict the local fire occurrence. The results illustrated that ZINB model was superior over the other three models (ZIP, PH and NBH) based on the result of AIC and SSR tests. LR test revealed that the negative binomial distribution was suitable to both the "count" portion of zero-inflated model and hurdle model. Furthermore, this paper concluded that the zero-inflated model could better fit the fire feature of the study area according to the hypotheses of the two types of models.
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Stem Cell Res Ther
December 2024
National Colorectal Disease CenterNanjing Hospital of Chinese Medicine, Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, Jiangsu, People's Republic of China.
Background: Complex perianal fistulas, challenging to treat and prone to recurrence, often require surgical intervention that may cause fecal incontinence and lower quality of life due to large surgical wounds and potential sphincter damage. Human umbilical cord-derived MSCs (hUC-MSCs) and their exosomes (hUCMSCs-Exo) may promote wound healing.
Methods: This study assessed the efficacy, mechanisms, and safety of these exosomes in treating complex perianal fistulas in SD rats.
BMC Geriatr
December 2024
Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic.
Introduction: Obesity in older adults is linked to various chronic conditions and decreased quality of life. Traditional physical activity guidelines often overlook the specific postures and movements that older adults engage in daily. This study aims to explore the compositional associations between posture-specific behaviours and obesity risk in younger (M = 67.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Science and Environment, Roskilde University, Universitetsvej 1, P.O. Box 260, DK-4000 Roskilde, Denmark. Electronic address:
The IR polarization spectrum of acetylacetone enol (AAe, (3Z)-4-hydroxy-3-penten-2-one) was recorded in the region 2000 - 450 cm using stretched polyethylene as an anisotropic solvent. The measured orientation factors were consistent with C molecular symmetry of AAe and provided an experimental distinction between in-plane and out-of-plane polarized spectral features. The results suggest the assignment of at least one previously unrecognized fundamental transition.
View Article and Find Full Text PDFMol Cell Endocrinol
December 2024
International Peace Maternity & Child Health Hospital, Shanghai Municipal Key Clinical Speciality, Institute of Embryo-Fetal Original Adult Disease, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China. Electronic address:
Endometriosis, a gynecological disorder marked by pelvic pain and infertility, has its pathogenesis and pathophysiology significantly influenced by epigenetics, as these factors have been well characterized. However, the role of RNA-mediated epigenetic regulation in endometriosis remains to be elucidated. In our study, we found that N4-acetylcytidine (acC) RNA modification and N-acetyltransferase 10 (NAT10) were significantly upregulated in endometrial lesions compared to eutopic endometrium.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Key Laboratory of Xin'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei, Anhui, PR China, 230038; Institute of Surgery, Anhui Academy of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, PR China, 230038. Electronic address:
Ethnopharmacological Relevance: Type 2 diabetes mellitus (T2DM) is a metabolic disease that can lead to complications affecting multiple organs, including the liver. Gegen Qinlian Decoction (GQD) has demonstrated considerable efficacy in the management of T2DM and its complications in accordance with the tenets of modern Chinese medicine. However, the molecular mechanism by which GQD alleviates diabetic liver injury is unclear.
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