The reconstruction problem for periodic (arbitrary profiled within a period) boundary between two homogeneous media is considered. Our approach to the solution of the inverse problem is based on the Tikhonov regularization technique, which requires successive selection of the boundaries on the basis of multiple solutions of the direct problem of wave diffraction by the candidate boundaries. The analytical numerical C method has been chosen as a simple but rather efficient tool for the direct problem solving. The scheme for numerical tests of algorithms and criteria for reconstruction accuracy have been suggested and verified. Results of numerical experiments that prove the validity of the approach are presented.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1364/JOSAA.31.001083 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Selecting the optimal dose for clinical development is especially problematic for drugs directed at CNS-specific targets. For drugs with a novel mechanism of action, these problems are often greater. We describe Xanamem's clinical pharmacology, including the approach to dose selection and proof-of-concept studies.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
UTMB, Galveston, TX, USA.
Background: The goal of this study is to examine how gender of research participants affects informants assessments of cognitive functioning in older adults. Informant assessments are important tools when clinicians diagnose cognitive decline and dementia and have been used to characterize highly impaired adults in population studies. Contextual and social factors for men and women in different countries may make informants more or less likely to report changes in functioning and cognitive declines at different levels of cognitive impairment.
View Article and Find Full Text PDFAttitudes toward scale-up of an Intensive Combination Approach to Rollback the Epidemic in Nigerian adolescents (iCARE) intervention for youth in Nigeria: results of a mixed methods early-implementation study.
Implement Sci Commun
January 2025
Feinberg School of Medicine, Northwestern University, Chicago, USA.
Background: Youth living with HIV (YLH) are disproportionately impacted by HIV with poor outcomes along the entire HIV care continuum. In a 2020-2022 pilot study, iCARE Nigeria, successfully tested a combination intervention incorporating mobile health technology and peer navigation to: 1) improve testing and linkage to HIV care for young men, especially young men who have sex with men (YMSM) and 2) improve medication adherence and treatment outcomes for YLH. The intervention was scaled up to 5 sites in 3 Nigerian cities.
View Article and Find Full Text PDFLearning with noisy labels via clean aware sharpness aware minimization.
Sci Rep
January 2025
School of Mechanical, Electrical, and Information Engineering, Putian University, Putian, 351100, China.
Noise label learning has attracted considerable attention owing to its ability to leverage large amounts of inexpensive and imprecise data. Sharpness aware minimization (SAM) has shown effective improvements in the generalization performance in the presence of noisy labels by introducing adversarial weight perturbations in the model parameter space. However, our experimental observations have shown that the SAM generalization bottleneck primarily stems from the difficulty of finding the correct adversarial perturbation amidst the noisy data.
View Article and Find Full Text PDFSleep and circadian disturbances in children with neurodevelopmental disorders.
Nat Rev Neurol
January 2025
Sleep Research Centre, Oasi Research Institute - IRCCS, Troina, Italy.
Sleep is essential for brain development and overall health, particularly in children with neurodevelopmental disorders (NDDs). Sleep disruptions can considerably impact brain structure and function, leading to dysfunction of neurotransmitter systems, metabolism, hormonal balance and inflammatory processes, potentially contributing to the pathophysiology of NDDs. This Review examines the prevalence, types and mechanisms of sleep disturbances in children with NDDs, including autism spectrum disorder, attention-deficit hyperactivity disorder and various genetic syndromes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!