The responsivity of optical fibers to refractive index can be enhanced using high-order skew rays compared with using meridional rays. Skew rays can have a much higher number of reflections with increased interaction length along the core-cladding interface, which gives rise to stronger interactions with the external medium. Reflection/transmission-type refractometric sensors based on twin-coupled-core and multimode fibers showed one/two orders of magnitude increase in responsivity with skew ray excitation. The responsivity and sensitivity for the two types are ~2000%/RIU, ~1400%/RIU, and 4.9×10⁻⁵ RIU, 7.0×10⁻⁵ RIU, respectively.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1364/OL.39.003822 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Descriptive Analysis of Preoperative Breast Reconstruction Patient Expectations Using the BREAST-Q Expectations Module.
Plast Surg (Oakv)
February 2025
Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Patient expectations have been shown to influence postoperative outcomes across surgical specialties. However, the impact of expectations in breast reconstruction is not well understood. The purpose of this project is to perform the first large-scale analysis and classification of BREAST-Q Expectations responses in patients undergoing implant-based reconstruction.
View Article and Find Full Text PDFInterferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells.
Nat Commun
January 2025
Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.
Interferon (IFN)-α is the earliest cytokine signature observed in individuals at risk for type 1 diabetes (T1D), but the effect of IFN-α on the antigen repertoire of HLA Class I (HLA-I) in pancreatic β-cells is unknown. Here we characterize the HLA-I antigen presentation in resting and IFN-α-exposed β-cells and find that IFN-α increases HLA-I expression and expands peptide repertoire to those derived from alternative mRNA splicing, protein cis-splicing and post-translational modifications. While the resting β-cell immunopeptidome is dominated by HLA-A-restricted peptides, IFN-α largely favors HLA-B and only marginally upregulates HLA-A, translating into increased HLA-B-restricted peptide presentation and activation of HLA-B-restricted CD8 T cells.
View Article and Find Full Text PDFBayesian fractional polynomial approach to quantile regression and variable selection with application in the analysis of blood pressure among US adults.
J Appl Stat
May 2024
Department of Mathematics, Brunel University London, Uxbridge, UK.
Although the fractional polynomials (FPs) can act as a concise and accurate formula for examining smooth relationships between response and predictors, modelling conditional mean functions observes the partial view of a distribution of response variable, as distributions of many response variables such as blood pressure (BP) measures are typically skew. Conditional quantile functions with FPs provide a comprehensive relationship between the response variable and its predictors, such as median and extremely high-BP measures that may be often required in practical data analysis generally. To the best of our knowledge, this is new in the literature.
View Article and Find Full Text PDFCodon bias, nucleotide selection, and genome size predict in situ bacterial growth rate and transcription in rewetted soil.
Proc Natl Acad Sci U S A
January 2025
Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA 94550.
In soils, the first rain after a prolonged dry period represents a major pulse event impacting soil microbial community function, yet we lack a full understanding of the genomic traits associated with the microbial response to rewetting. Genomic traits such as codon usage bias and genome size have been linked to bacterial growth in soils-however, often through measurements in culture. Here, we used metagenome-assembled genomes (MAGs) with O-water stable isotope probing and metatranscriptomics to track genomic traits associated with growth and transcription of soil microorganisms over one week following rewetting of a grassland soil.
View Article and Find Full Text PDFModifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials.
JAMA Psychiatry
January 2025
Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco.
Importance: There is unprecedented clinician, industry, and patient interest in the therapeutic development of psychedelic drugs. This is due to a combination of promising clinical trial results, positive media coverage, and the lack of novel pharmacologic treatments for psychiatric disorders in recent decades. However, the field faces a key methodological challenge: masking participants to treatment conditions in psychedelic clinical trials has been largely unsuccessful.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!