Objective: To assess the frequency of spontaneous changes of bacterial strains in patients with untreated asymptomatic bacteriuria.
Design: Retrospective analysis of samples from all patients with renal scarring and random sample of patients with normal kidneys.
Setting: Outpatient clinic for children with urinary tract infections.
Patients: 54 Girls aged 3.3-15.5 years with untreated asymptomatic bacteriuria caused by Escherichia coli.
Intervention: None.
End Point: Change in bacterial strain.
Measurements And Results: Serotyping and electrophoretic analysis of sequential bacterial isolates, representing 151 patient years of untreated asymptomatic bacteriuria. A total of 24 changes of strain were identified. Eleven were related to medical interference such as treatment of other infections with antibiotics.
Conclusions: Spontaneous changes of strain were uncommon, one change in 11.6 patient years, and thus are not a characteristic feature of the course of asymptomatic bacteriuria.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1836156 | PMC |
| http://dx.doi.org/10.1136/bmj.298.6677.853 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Congenital Bullous Syphilis: A Case Report from Italy and a Comprehensive Literature Review.
Medicina (Kaunas)
January 2025
Department of Health Science, University of Eastern Piedmont, 28100 Novara, Italy.
Congenital syphilis remains a significant global health concern, with severe morbidity and mortality if undiagnosed and untreated. Although many infants appear asymptomatic at birth, subtle clinical signs-including bullous lesions (congenital bullous syphilis, also known as pemphigus syphiliticus)-may facilitate early detection. Recognizing this rare manifestation is crucial for timely intervention, reducing serious outcomes.
View Article and Find Full Text PDFEvaluation of Awareness, Knowledge, Attitude and Practices Related to Toxoplasmosis Among Females in Algeria.
Vet Sci
December 2024
Laboratoire d'Exploration et Valorisation des Écosystèmes Steppiques, Faculty of Natural and Life Sciences, University of Djelfa, PO Box 3117, Djelfa 17000, Algeria.
Toxoplasmosis is a major veterinary and public health issue affecting humans and animals, where felids represent the definitive hosts of the causative agent . While the infections are mostly asymptomatic, the disease could be severe in immune-compromised patients and pregnant women. This study was conducted to evaluate the level of knowledge, practice, and attitude toward this disease among a sample of Algerian women.
View Article and Find Full Text PDFEfficacy of ramucirumab combined with erlotinib or osimertinib in untreated EGFR-mutated NSCLC patients with asymptomatic brain metastases: insights from molecular biomarkers in the RELAY-brain trial.
Invest New Drugs
January 2025
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Background: The RELAY-Brain trial examined the clinical utility and survival impacts of ramucirumab (RAM) combined with epidermal growth factor receptor (EGFR)-TKI in patients with EGFR-mutated non-small-cell lung cancer (NSCLC) with brain metastases. Although RAM combined with erlotinib (ERL) is known to have clinical benefits, the benefits in patients with baseline brain metastases remain unclear. This report examined the long-term follow-up data (Japan Registry of Clinical Trials: jRCTs2051190027) of the same patients, analyzing relevant biomarkers from tumor and plasma samples.
View Article and Find Full Text PDFPgp3 monoclonal antibody inhibits the pathogenicity of Chlamydia muridarum to the genital tract of mice.
Int Immunopharmacol
January 2025
Department of Dermatovenereology, Tianjin Medical University General Hospital/Tianjin Institute of Sexually Transmitted Disease, Tianjin 300052, China. Electronic address:
Background: Chlamydia trachomatis (Ct) is the leading cause of tubal inflammation in women, with a high tendency for persistent asymptomatic infections. Antibiotics are currently the primary treatment for Ct infections of the reproductive tract. However, mounting evidence indicates an increasing incidence of persistent infections and recurrence due to antibiotic treatment failure, highlighting the urgent need for novel therapeutic approaches.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!