AI Article Synopsis

  • Erythema nodosum leprosum (ENL) is a type-III hypersensitivity reaction often seen in lepromatous leprosy cases.
  • ENL manifests as inflamed nodules and papules on the skin, with rare variants resembling conditions like pemphigus or Sweet's syndrome.
  • A specific case of persistent ENL was diagnosed in a 52-year-old woman through skin biopsy and histopathological analysis.

Article Abstract

Erythema nodosum leprosum (ENL) or Type-2 lepra reaction is a manifestation of type-III hypersensitivity response, and usually occurs in certain cases of lepromatous and borderline lepromatous leprosy. ENL may present as widespread crops of erythematous, inflamed nodules and papules. Rare variants of ENL mimicking pemphigus or Sweet's syndrome (SS) have been documented. Here, we report an unusual case of persistent ENL in a 52-year-old lady, which we could diagnose with the help of skin biopsy and histopathological examination.

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