Objective: Ventriculoperitoneal shunts (VPS) are a common treatment for hydrocephalus. Placement of the distal abdominal catheter can be difficult in the setting of advanced age, previous abdominal surgeries, obesity, or chronic illnesses. At our institute, complex patients are treated using a multidisciplinary team of a neurosurgeon and a laparoscopic surgeon. We evaluated the influence on prognosis of a laparoscopically assisted VPS placement using a single-port technique as compared with the conventional mini-laparotomy approach.
Methods: Between 2006 and 2010, 302 patients were operated for hydrocephalus or shunt dysfunction. Among these, a total of 48 patients were operated on using the single-trocar laparoscopy. Neurosurgeons and laparoscopic surgeons logged the presenting symptoms, past medical history, chronic diseases, past surgical procedures, the actual surgical procedure and intraoperative findings. Outcome data were collected at several time points, using several independent outcome parameters.
Results: The laparoscopic group was significantly older, had more chronic diseases, and had more prior abdominal and shunt operations. However, this group had the same outcome as the minilaparotomy group..
Conclusions: The outcome of elderly patients, patients with chronic diseases and obesity, and patients who underwent previous abdominal or shunt operations equals the outcome of young, otherwise healthy patients, if the laparoscopic single-port technique for distal catheter placement during VPS procedure is used. The laparoscopic technique reduces surgical complications.
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http://dx.doi.org/10.1055/s-0034-1371516 | DOI Listing |
Adv Ther
December 2024
GSK, US Value Evidence and Outcomes, Collegeville, PA, 19426-0989, USA.
Introduction: Chronic obstructive pulmonary disease (COPD) is associated with exacerbations which can reduce quality of life and increase mortality. Single-inhaler triple therapy (SITT) is recommended for maintenance treatment of COPD among patients experiencing exacerbations despite dual-therapy use. This real-world comparative effectiveness study compared the impact of SITTs, fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI), and budesonide/glycopyrrolate/formoterol fumarate (BUD/GLY/FORM), on COPD exacerbations and mortality.
View Article and Find Full Text PDFInt J Health Plann Manage
December 2024
Centre for Global Chronic Conditions, London School of Hygiene & Tropical Medicine, London, UK.
Background: Reducing inequities in hypertension control among those affected in low- and middle-income countries requires person-centred health system responses based on a contextualised understanding of the choices and care pathways taken by those who rely on the services provided, particularly those from poor and marginalised communities. We examine patterns of care seeking and pathways followed by individuals with hypertension from low-income households in the Philippines and Malaysia. This study aims to fill a significant gap in the literature by analysing the stages at which individuals make decisions that may affect the successful control of their blood pressure.
View Article and Find Full Text PDFInt Urol Nephrol
December 2024
Nishtar Medical University, Multan, Pakistan.
Renal fibrosis is a hallmark of chronic kidney disease, characterized by the excessive accumulation of extracellular matrix proteins. Sulforaphane, a potent antioxidant found in cruciferous vegetables, has shown promise in targeting renal fibrosis. By inhibiting fibrotic pathways, such as TGF-β signaling, and promoting antioxidant defenses, sulforaphane may offer a novel therapeutic strategy for mitigating kidney damage and slowing disease progression.
View Article and Find Full Text PDFInt Urol Nephrol
December 2024
Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Purpose: With the increasing demand for dialysis, there is a growing emphasis on patient-centered care. This study investigated patients' satisfaction levels with peritoneal dialysis (PD) and hemodialysis (HD) care in Iran.
Methods: A cross-sectional multicenter study was conducted among 346 patients with chronic kidney disease (CKD) covered by the Iran Health Insurance Organization who received dialysis services from October to December 2022 across the country.
J Pediatr Psychol
December 2024
Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at the University of California, Los Angeles (UCLA), Los Angeles, CA, United States.
Objective: Adolescents and young adults with chronic diseases face unique challenges during the college years and may consume alcohol and other substances to cope with stressors. This study aimed to assess the patterns of substance use and to determine psychosocial correlates of these behaviors among college youth with type 1 diabetes (T1D).
Methods: College youth with T1D were recruited via social media and direct outreach into a web-based study.
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