AI Article Synopsis
- Percutaneous coronary intervention (PCI) is commonly used for treating coronary artery disease, but its effectiveness in reducing restenosis and improving quality of life has been limited.
- A clinical trial assessed the impact of the Huxin Formula, a modified Chinese medicine, on patients undergoing PCI, revealing no significant differences in primary outcomes between the treatment and control groups.
- However, patients with good ejection fractions and those with unstable angina reported better quality of life scores after using the Huxin Formula, with no serious side effects observed, suggesting it may be a safe option for certain patients post-PCI.
Article Abstract
Percutaneous coronary intervention (PCI) is widely used in clinical treatment of coronary artery disease. However, the effects of PCI on preventing restenosis after revascularization and improving the quality of life were not satisfying. Huxin Formula is formulated by modifying an experienced Chinese medicine formula and has been widely used in clinical practice due to its marked effects on coronary heart disease. A multicentre double-blind randomized controlled clinical trial was designed to evaluate the effects and safety of Huxin Formula in patients undergoing PCI. Our results showed that there was no significant difference between the two groups in main outcomes. For patients with ejection fraction (EF) >50%, score of the quality of life scale was higher in treatment group compared with control group. For patients with unstable angina, score of the quality of life scale in 360 days was significantly higher in treatment group compared with control group (P < 0.05). No obvious adverse reaction was found in the use of Huxin Formula. In conclusion, Huxin Formula, believed to be a safe treatment for patients after PCI, has benefits in improving the quality of life in patients with unstable angina though it failed to show superiority in primary and secondary outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058264 | PMC |
| http://dx.doi.org/10.1155/2014/143064 | DOI Listing |
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