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Abnormal network homogeneity in patients with bipolar disorder in attention network.
Brain Imaging Behav
January 2025
Key Laboratory of Adolescent Cyberpsychology and Behavior (Ministry of Education), Wuhan, China.
Bipolar disorder (BD) is a complex psychiatric condition marked by significant mood fluctuations that deeply affect quality of life. Understanding the neural mechanisms underlying BD is critical for improving diagnostic accuracy and developing more effective treatments. This study utilized resting-state functional magnetic resonance imaging (rs-fMRI) to investigate functional connectivity within the ventral and dorsal attention networks in 52 patients with BD and 51 healthy controls.
View Article and Find Full Text PDFBioconversion of mustard oil cake for production of lipase, optimization and direct immobilization from solid-state fermentation extract.
Prep Biochem Biotechnol
January 2025
Department of Physical Science, Sant Baba Bagh Singh University, Jalandhar, Punjab, India.
Fungal lipases are the leading industrial biocatalyst due to their broad applications, but high cost limits their commercial usage. The low-cost agri-residues substrates can reduce the cost of lipase production. However, the compatibility of agri-residue with fungal species, recovery process of lipase and stability of the enzyme are crucial steps.
View Article and Find Full Text PDFDiagnostic value of 11C-Methionine PET-CT imaging in persistent or recurrent Cushing's disease after surgery.
J Clin Endocrinol Metab
January 2025
Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc UCL, Bruxelles, Belgium.
Introduction: Equivocal or negative pituitary magnetic resonance imaging (MRI) findings raise a significant challenge in the management of persistent or recurrent Cushing's disease (CD), compromising the chances of success of a further transsphenoidal surgery (TSS). The aim of our study was to determine the diagnostic utility of 11C-methionine (MET) positron emission tomography coupled with computerized tomography (PET/CT) in localizing the residual or relapsing corticotroph adenoma.
Methods: We retrospectively analyzed the results of 11C-MET PET/CT performed in two tertiary medical centers between May 2002 and November 2023 in 22 patients with a persisting or recurrent CD after initial TSS and equivocal or negative pituitary MRI findings.
Automatic classification of temporomandibular joint disorders by magnetic resonance imaging and convolutional neural networks.
J Dent Sci
January 2025
Institute of Statistics, National Yang Ming Chiao Tung University, Hsinchu City, Taiwan.
Background/purpose: In this study, we utilized magnetic resonance imaging data of the temporomandibular joint, collected from the Division of Oral and Maxillofacial Surgery at Taipei Veterans General Hospital. Our research focuses on the classification and severity analysis of temporomandibular joint disease using convolutional neural networks.
Materials And Methods: In gray-scale image series, the most critical features often lie within the articular disc cartilage, situated at the junction of the temporal bone and the condyles.
Study of dynamic brain function in irritable bowel syndrome via Hidden Markov Modeling.
Front Neurosci
January 2025
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Background And Purpose: Irritable bowel syndrome (IBS) is a common bowel-brain interaction disorder whose pathogenesis is unclear. Many studies have investigated abnormal changes in brain function in IBS patients. In this study, we analyzed the dynamic changes in brain function in IBS patients using a Hidden Markov Model (HMM).
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