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| http://dx.doi.org/10.1136/bmj.298.6676.830 | DOI Listing |
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Low clinical activity score, 'progressive' thyroid eye disease: presentations of 1439 patients from a tertiary centre in Hong Kong.
Br J Ophthalmol
January 2025
Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, Hong Kong
Background: To report the presenting clinical, serological and treatment profiles of 1439 patients with thyroid eye disease (TED) from a tertiary centre in Hong Kong.
Study Populations: Consecutive patients with TED presented to the Thyroid Eye Clinic (TEC), the Chinese University of Hong Kong between 2014 and 2023.
Methods: Prospective cohort and masked review of medical records and orbital images.
A Case of Euthyroid Graves' Ophthalmopathy With Negative Thyroid Antibodies.
Cureus
November 2024
Geriatrics, American Hospital Dubai, Dubai, ARE.
Grave's ophthalmopathy is a prevalent complication of Grave's disease. In this case report, we present a case of an 84-year-old female patient with no symptoms of hyperthyroidism except that of Grave's ophthalmopathy. The patient's thyroid profile was normal, and both thyroid receptor antibodies and thyroid-stimulating immunoglobulins were negative.
View Article and Find Full Text PDFTeprotumumab versus intravenous methylprednisolone in thyroid eye disease: A systematic review.
Oman J Ophthalmol
October 2024
Department of Ophthalmology, Aster DM Healthcare, Dubai, UAE.
Thyroid eye disease (TED), also known as thyroid-associated ophthalmopathy, is an autoimmune disorder caused due to a complex interplay between autoantigens including the thyroid-stimulating hormone receptor and the insulin-like growth factor-I receptor. TED is characterized by progressive proptosis or diplopia. This systematic review aimed to compare the efficacy of the newer monoclonal antibody - teprotumumab and intravenous methylprednisolone (IVMP) in TED patients.
View Article and Find Full Text PDFRheumatoid Arthritis: A Rare Cause of Pachymeningitis and Optic Neuritis.
Eur J Case Rep Intern Med
November 2024
Department of Internal Medicine, Tower Health, Reading Hospital, West Reading, USA.
Introduction: Rheumatoid pachymeningitis and optic neuritis are rare complications of rheumatoid arthritis (RA) and are a diagnosis of exclusion.
Case Description: A 75-year-old male with a history of seronegative RA presented to the emergency department with left eye pain and blurry vision lasting two days. He had been diagnosed with seronegative RA around nine months previously.
Propylthiouracil-induced vasculitis with alveolar hemorrhage after 31 years of treatment: a case report.
Clin Diabetes Endocrinol
November 2024
Jenin Governmental Hospital, Jenin, West Bank, Palestine.
Background: Propylthiouracil is an antithyroid medication that is associated with ANCA positivity, often in the absence of clinically overt vasculitis. Propylthiouracil-induced ANCA-associated vasculitis (AAV) is characterized by multiple antigenicity and presents similarly to other forms of drug-induced vasculitis.
Case Presentation: We report a case of a 49-year-old woman who developed propylthiouracil-induced AAV after 31 years of intermittent therapy.
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