Background: Chronic pain is likely to lead to depressive symptoms, but the nature of this relationship is not completely clear. The aim of the present study is to analyze the role of activity restriction in the pain-depression relationship in older people, and to test the hypothesis that this role is more relevant in community-dwelling older people than in nursing home residents.

Method: Depressive symptoms, pain intensity, and activity restriction were measured in a sample of 208 older adults with osteoarthritis, 102 living in nursing homes (NH), and 106 in the community. Analyses were carried out using moderation and moderated mediation analyses approach, treating activity restriction as a confounder.

Results: RESULTS showed a significant confounding effect of activity restriction, interaction effect between pain intensity and activity restriction on depression, and modifying effect of pain intensity on depression by adding activity restriction into the model. These results suggest a potential mediating and moderating effects of activity restriction. Moreover, analyses suggest that, surprisingly, the strength of the mediation could be higher in nursing homes.

Conclusions: Overall, it may be that what is really important to emotional well-being is not so much pain itself, but rather the way in which the pain alters older people's lives. The greater strength of the mediation in NH might be understood within the scope of self-determination theory. Generally speaking, the NH context has been considered as a coercive setting, promoting non-autonomous orientation. In this context, when events are objectively coercive, people may lack perceived autonomy and hence be at greater risk of depression.

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610214000970DOI Listing

Publication Analysis

Top Keywords

activity restriction
32
pain intensity
12
older adults
8
nursing homes
8
activity
8
role activity
8
restriction
8
depressive symptoms
8
older people
8
intensity activity
8

Similar Publications

Background: Developing interventions along with the population of interest using systems thinking is a promising method to address the underlying system dynamics of overweight. The purpose of this study is twofold: to gain insight into the perspectives of adolescents regarding: (1) the system dynamics of energy balance-related behaviours (EBRBs) (physical activity, screen use, sleep behaviour and dietary behaviour); and (2) underlying mechanisms and overarching drivers of unhealthy EBRBs.

Methods: We conducted Participatory Action Research (PAR) to map the system dynamics of EBRBs together with adolescents aged 10-14 years old living in a lower socioeconomic, ethnically diverse neighbourhood in Amsterdam East, the Netherlands.

View Article and Find Full Text PDF

Metabolic rewiring underlies effective macrophages defense to respond disease microenvironment. However, the underlying mechanisms driving metabolic rewiring to enhance macrophage effector functions remain unclear. Here, we demonstrated that the metabolic reprogramming in inflammatory macrophages depended on the acetylation of CLYBL, a citramalyl-CoA lyase, at lysine 154 (K154), and blocking CLYBL-K154 acetylation restricted the release of pro-inflammatory factors.

View Article and Find Full Text PDF

Background Recommendations regarding long-term postoperative activity are intended to prevent adverse events, but no common policy or best practice exists among ophthalmologists for pediatric patients. We surveyed ophthalmologists on their postoperative guidelines after the one-month postoperative period following childhood cataract and glaucoma surgeries. Methods A 28-question anonymous Qualtrics survey was distributed via listservs and social media.

View Article and Find Full Text PDF

Cellulose/covalent organic framework aerogel for efficient removal of Cr(VI): Performance and mechanism study.

Int J Biol Macromol

January 2025

Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products, Southwest Forestry University, Kunming 650224, Yunnan, China. Electronic address:

Cellulose composites have exceptional qualities, particularly in removing heavy metal ions. Nevertheless, these materials' poor mechanical qualities and the restricted exposure of surface-active sites reduce the effectiveness of their removal. The removal efficiency of adsorbent materials largely depends on their macroscopic structural characteristics.

View Article and Find Full Text PDF

Enhancing curcumin stability and bioavailability through chickpea protein isolate-citrus pectin conjugate emulsions: Targeted delivery and gut microecology modulation.

Int J Biol Macromol

January 2025

School of Food Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, China; Key Laboratory of Characteristics Agricultural Product Processing and Quality Control (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Shihezi University, Shihezi, Xinjiang 832000, China; Key Laboratory for Food Nutrition and Safety Control of Xinjiang Production and Construction Corps, Shihezi University, Shihezi, Xinjiang 832000, China. Electronic address:

The limited solubility, rapid metabolism, and poor bioavailability of curcumin restrict its application. In this study, we synthesized chickpea protein isolate (CPI)-citrus pectin (CP) conjugates to prepare an emulsion delivery system that enhances the stability and bioavailability of curcumin. The CPI-CP emulsion achieved a curcumin encapsulation efficiency of 86.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!