The present investigation evaluated the efficacy of a botanical supplement that delivered a concentrated dose of Echinacea purpurea (8 grams day(-1)). The participants were 13 apparently healthy, recreationally active college students (VO2 max: 51 mL O2/kg∗min). The participants were provided with a 30-day supplementation regime. Data regarding maximum aerobic capacity was collected through pre- and posttesting surrounding the 30-day supplementation regime. The participants were instructed to maintain normal levels of physical activity and exercise during the experimental period. The levels of physical activity and exercise were monitored via the Leisure and Physical Activity Survey. The participants did not report any significant increases in aerobic physical activity or exercise during the supplementation period. Paired samples t-test analysis did not reveal a significant difference in maximum aerobic capacity, t(12) = 0.67, P = .516. Presupplementation maximum aerobic capacity (M = 51.0, SD = 6.8) was similar to postsupplementation values (M = 51.8, SD = 6.5). This study suggests that botanical supplements containing a concentrated dose of Echinacea purpurea is not an effective intervention to increase aerobic capacity of recreationally active individuals.
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http://dx.doi.org/10.1155/2014/149549 | DOI Listing |
Gan To Kagaku Ryoho
February 2025
Dept. of Rehabilitation Medicine, Keio University School of Medicine.
As cancer becomes more of a chronic condition, cancer rehabilitation care aimed at maintaining and improving patients' quality of life(QOL)is becoming increasingly important. Cancer rehabilitation care addresses both disabilities caused by cancer itself and those that arise during the treatment process. Cancer rehabilitation is divided into four phases-preventive, restorative, supportive, and palliative.
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March 2025
National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology, Engineering Research Center of Beijing, Beijing University of Technology, Beijing 100124, China.
The accumulation of micro/nanoplastics in wastewater significantly hinders denitrification in biological wastewater treatment systems, yet the intrinsic mechanisms are not fully understood. Herein, we combined signal molecule monitoring, electrochemical characterization and multi-omics analysis to investigate how quorum sensing (QS)-mediated microbial interactions influence denitrification in aerobic granular sludge systems. Results showed that after 90-day exposure to micro/nanoplastics, cross-talk between multiple signal molecules significantly declined, thereby disrupting the QS system to opportunely sense changes in the external environment.
View Article and Find Full Text PDFSci Adv
March 2025
Cancer Ecosystems Program, Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, Sydney, New South Wales, Australia.
Pancreatic cancer (PC) is a highly metastatic malignancy. More than 80% of patients with PC present with advanced-stage disease, preventing potentially curative surgery. The neuropeptide Y (NPY) system, best known for its role in controlling energy homeostasis, has also been shown to promote tumorigenesis in a range of cancer types, but its role in PC has yet to be explored.
View Article and Find Full Text PDFCells
February 2025
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Preclinical studies have shown that the blood from female mice exposed weekly to magnetic fields inhibited breast cancer growth. This double-blind randomized controlled trial investigated whether analogous magnetic therapy could produce similar anticancer sera from human subjects. Twenty-six healthy adult females (ages 30-45) were assigned to either a magnetic therapy group, receiving twice weekly 1 mT magnetic exposures (10 min/session) for 4 weeks, or a control group, who underwent identical sham exposure.
View Article and Find Full Text PDFERJ Open Res
March 2025
University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, The Netherlands.
Rationale: Bronchoscopic lung volume reduction treatment using endobronchial valves (EBV) is an effective treatment for severe COPD patients by improving lung function and quality of life. However, little is known about its effects on systemic inflammation. Therefore, the aim of our study was to investigate whether EBV treatment impacts the inflammatory cytokine profile.
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