Membrane bioincompatibility was demonstrated by successive white blood cell counts and C3a generation. Pulse wave analysis was obtained by applanation tonometry (SphygmoCor) in a sequential way: basal, after 30 minutes with nul ultrafiltration, and after a complete dialysis with ultrafiltration. At 15 minutes of haemodialysis, significant decrease in leukocyte count occurred: 6801 ± 1186 versus 4412 ± 1333 (P < 0.001), while C3a levels sharply increased from 427 ± 269 to 3501 ± 1638 ng/mL (P < 0.000). No changes were observed in augmentation index without ultrafiltration: 26.1 ± 11.1 versus 26.6 ± 12.4. Only aortic systolic blood pressure was lower at 15 minutes: 120.1 ± 17.7 versus 110.4 ± 25.8 mmHg (P = 0.009), in agreement with a reduction in brachial systolic blood pressure: 135.1 ± 18.1 versus 122.7 ± 27.4 mmHg (P = 0.01), without changes in aortic or brachial diastolic blood pressure. Important changes in pulse wave analysis were observed after a complete haemodialysis session: augmentation index 29.9 ± 10.1 versus 18.6 ± 15.0, aortic systolic blood pressure 139.8 ± 25.5 versus 119.4 ± 28.5 mmHg (P < 0.00), without changes in aortic diastolic blood pressure. In summary, haemodialysis with cellulose diacetate acutely induced a transient state of immunoactivation due to bioincompatibility, this phenomenon was nondetectable by pulse wave analysis. Complete haemodialysis session led to important changes in pulse wave analysis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045438 | PMC |
| http://dx.doi.org/10.5402/2013/892315 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The broad spectrum of clinical manifestations caused by peripheral arterial disease [PAD] and the morphologic heterogeneity of associated atherosclerotic lesions present a considerable management challenge. Endovascular interventions are recognized an effective treatment for PAD. Within this revascularization strategy the role of atherectomy debulking modalities continue to evolve.
View Article and Find Full Text PDFUnderstanding low-threshold mode-locking at multi-GHz repetition rate.
Light Sci Appl
January 2025
Russell Centre for Advanced Lightwave Science, Shanghai Institute of Optics and Fine Mechanics and Hangzhou Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai, 201800, China.
Continuous-wave mode-locking at multi-GHz repetition rates is achieved in an ultrashort laser cavity at critical pulse energies 100 times lower than predicted by conventional theory. The authors reveal that dynamic gain depletion and recovery between consecutive round-trips is the key factor behind a low-pulse-energy transition from Q-switched mode-locking (QSML) to continuous-wave mode-locking (CWML). As well as providing new insight into gain dynamics, the results suggest a practical route to low-threshold lasing at very high-repetition rates.
View Article and Find Full Text PDFInvestigations of segmental arterial stiffness in a cross-sectional study on young adult male trained swimmers, cyclists, and non-trained men.
Physiol Rep
January 2025
Faculty of Environmental Symbiotic Sciences, Prefectural University of Kumamoto, Kumamoto, Japan.
Contrary to cardiovascular risk reductions by aerobic exercise, arterial stiffness, as assessed by brachial-ankle pulse wave velocity (PWV), is higher in swimmers and controls than in other aerobically trained individuals. The main muscles actively recruited in swimming are in the upper limbs, so this study aimed to investigate heart-brachial PWV in swimmers and to compare arterial stiffness indices between modes and measurement localities. Subjects comprised 60 individuals (18-22 years), including 20 untrained controls (Con), 20 aerobically trained cyclists (Aero), and 20 swimmers (Swim).
View Article and Find Full Text PDFEnhancing Inflammatory Factors, Nitric Oxide, and Arterial Stiffness Through Aquatic Walking for Amelioration and Disease Prevention: Targeting in Obese Elderly Women.
Mediators Inflamm
January 2025
Laboratory of Sports Conditioning: Nutrition Biochemistry and Neuroscience, Department of Sport Science, College of Arts and Sports, University of Seoul, 163 Seoulsiripdaero, Dongdaemun-gu, Seoul 02504, Republic of Korea.
In elderly women, hormonal changes lead to elevated body fat content, which results in elevated levels of vascular inflammatory factors, thereby increasing the risk of cardiovascular diseases (CVDs) associated with endothelial dysfunction. Regular physical exercises tend to keep these in check and are protective to the body. Aerobic exercise has been reported to improve CVD in obese elderly women; in this regard, aquatic exercises have been demonstrated to be more efficient in energy metabolism than land-based exercise.
View Article and Find Full Text PDFCorrelations of the triglyceride-glucose index and modified indices with arterial stiffness in overweight or obese adults.
Front Endocrinol (Lausanne)
January 2025
Department of Endocrinology and Metabolism, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Background: Insulin resistance (IR) contributes substantially to the development of cardiovascular disease (CVD) and metabolic disorders, particularly obesity. The homeostatic model assessment of IR is a prevalent IR indicator, but insulin measurement is quite impractical for widely use. Given its convenience and accessibility, the triglyceride-glucose (TyG) index, along with modified indices such as the triglyceride-glucose-waist circumference (TyG-WC) and triglyceride-glucose-waist-height ratio (TyG-WHtR), are gaining recognition as practical tools for assessing IR.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!