Angiomatosis or diffuse hemangioma is a very rare benign vascular tumor, consisting of blood and lymphatic channels growing diffusely in the breast parenchyma. We report a case of diffuse breast angiomatosis in a 34-year-old woman with pubertal anisomastia. Ultrasound raised the suspicion of vascular tumor, by showing large cystic spaces separated by septae with moderate blood flow, similar to those found in cystic lymphangioma. We discuss the imaging (mammography, ultrasound, and MRI) and pathologic findings, with a brief review of the literature.
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