Selection of aptamers targeting the sialic acid receptor of hemagglutinin by epitope-specific SELEX.

Chem Commun (Camb)

Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan.

Published: August 2014

A new SELEX scheme is proposed for the selection of aptamers targeting a specific epitope of a native protein. Anti-sialic acid receptor (SAR) aptamers that inhibit H1 hemagglutination at a low picomole dose are selected accordingly.

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Source
http://dx.doi.org/10.1039/c4cc03116dDOI Listing

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