Simultaneous testing of erythrocyte sedimentation rate and C-reactive protein: increased expenditure without demonstrable benefit.

We analyzed the practice of paired erythrocyte sedimentation rate and C-reactive protein testing when evaluating fever or inflammation. In our hospital, this resulted in additional charges of $250000-$400000/year without demonstrable added benefit to patient care. Extrapolating our results, we estimate reducing this practice could save up to $300000000 nationally.