Geographical patterns in antimicrobial resistance of acinetobacter in clinical isolates.

J Clin Diagn Res

Director Professor, Department of Microbiology, Maulana Azad Medical College, New Delhi, India .

Published: April 2014

AI Article Synopsis

  • Acinetobacter spp. poses a significant risk to healthcare due to its multidrug resistance, prompting a study to analyze resistance patterns among patients in a hospital setting and compare them with findings from India and other countries.
  • Over one year, 5,593 clinical samples were tested for antimicrobial resistance in Acinetobacter spp., using Modified Stoke's method, and results were statistically analyzed for sensitivity and resistance percentages.
  • The results revealed high levels of multidrug resistance in Acinetobacter, consistent with other research, highlighting the urgent need to identify the genetic mechanisms behind this resistance.

Article Abstract

Objectives: Acinetobacter spp. has emerged as a threat to the healthcare workers throughout the globe, owing to its property of multidrug resistance. The aim of the present study was to evaluate the antimicrobial resistance patterns of Acinetobacter spp. among indoor and out patients in our hospital and compare the resistance patterns in India and abroad.

Materials And Methods: In this retrospective study, which was carried out between Over a period of one year, a total of 5593 clinical specimens of pus and purulent fluids were examined and antimicrobial resistance pattern for Acinetobacter spp. using Modified Stoke's were evaluated. Also a comparison was done with the other similar studies.

Statistical Analysis: Using the proportions of sensitive and resistant, the statistical analysis was done. The total, mean and percentage were calculated by using SPSS.

Results: A high level of antimicrobial multidrug-resistance was found in almost all the clinical isolate. Our study was also found to be concordant with the results of other studies.

Conclusion: There is an emerging need for identification of the genes and mechanisms for multidrug resistance among Acinetobacter spp.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064900PMC
http://dx.doi.org/10.7860/JCDR/2014/8590.4235DOI Listing

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