We report a challenging case of a 32-year-old patient in New York Heart Association (NYHA) class IV with pulmonary atresia, ventricular septal defect, a left aortopulmonary collateral artery, a right modified Blalock-Taussing shunt, and a gigantic aneurysm of the ascending aorta with severe aortic valve insufficiency. A combined Rastelli and Bentall procedure was performed by a joint adult and pediatric cardiovascular surgery team. One year after the operation, the patient is in NYHA class I, working full time.

Download full-text PDF

Source
http://dx.doi.org/10.1177/2150135114526419DOI Listing

Publication Analysis

Top Keywords

combined rastelli
8
rastelli bentall
8
pulmonary atresia
8
atresia ventricular
8
ventricular septal
8
septal defect
8
aortopulmonary collateral
8
collateral artery
8
ascending aorta
8
nyha class
8

Similar Publications

This study investigated the combined effects of adding niobium-fluoride (NbF) nanoparticles to a pit-and-fissure sealant. One resin sealant was reinforced with varying amounts of nanoparticles (0.3, 0.

View Article and Find Full Text PDF

Congenitally corrected transposition of the great arteries (ccTGA) is an infrequent and complex congenital malformation, which accounts for approximately 0.5% of all congenital heart defects. This defect is characterized by both atrioventricular and ventriculoarterial discordance, with the right atrium connected to the morphological left ventricle (LV), ejecting blood into the pulmonary artery, while the left atrium is connected to the morphological right ventricle (RV), ejecting blood into the aorta.

View Article and Find Full Text PDF

Prostate cancer (PCA) is one of the most prevalent types of male cancers. While current treatments for early-stage PCA are available, their efficacy is limited in advanced PCA, mainly due to drug resistance or low efficacy. In this context, novel valuable therapeutic opportunities may arise from the combined inhibition of histone deacetylase 6 (HDAC6) and heat shock protein 90 (Hsp90).

View Article and Find Full Text PDF

Unlabelled: A quantum-light source that delivers photons with a high brightness and a high degree of entanglement is fundamental for the development of efficient entanglement-based quantum-key distribution systems. Among all possible candidates, epitaxial quantum dots are currently emerging as one of the brightest sources of highly entangled photons. However, the optimization of both brightness and entanglement currently requires different technologies that are difficult to combine in a scalable manner.

View Article and Find Full Text PDF

Loss of Calpain 3 dysregulates store-operated calcium entry and its exercise response in mice.

FASEB J

July 2024

Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA.

Article Synopsis
  • Limb-Girdle Muscular Dystrophy R1/2A (LGMD R1/2A) is linked to mutations in the CAPN3 gene, which encodes Calpain 3, a protease critical for muscle function and calcium regulation.
  • Research using both Capn3 deficient (C3KO) and wild-type (WT) mice revealed that the absence of Calpain 3 resulted in increased resting calcium levels and altered Store-Operated Calcium Entry (SOCE) activity.
  • After exercise, C3KO mice demonstrated reduced muscle force and impaired calcium dynamics, highlighting that the dysregulation of SOCE due to the loss of Calpain 3 contributes significantly to LGMD R1/2
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!