[Study on the chemical constituents of the PTP 1B inhibitory effective parts of Paeoniae Rubra Radix].

Objective: To study the chemical constituents of the PTP 1B inhibitory effective parts of Paeoniae Rubra Radix.

Methods: The effective part of Paeoniae Rubra Radix was enriched by Sephadex LH-20. Compounds were isolated by various column chromatography and their structures were elucidated through spectroscopic analysis.

Results: Thirteen compounds were identified as: benzoylpaeoniflorin(1), albiflorin(2), paeoniflorigenone(3), methyl gallate(4), adenosine(5),2-amino adenosine(6), 3,3'-Di-O-methylellagic acid(7), 3,3',4-trimethyl ellagic acid(8), dihydrokaempferol(9), glycerol(10), dibutyl phthalate(11).

Conclusion: Compounds 5-11 are obtained from this plant for the first time.