AI Article Synopsis
- An emerging pathogen, Bordetella holmesii, is being linked to more cases resembling pertussis, or whooping cough.
- Analysis of the genomes from 9 clinical isolates reveals that they are genetically similar and lack the virulence factors typically seen in Bordetella pertussis.
- The genomic information can be used to develop new markers for identifying B. holmesii.
Article Abstract
An increasing number of pertussis-like cases are attributed to the emergent pathogen Bordetella holmesii. The genomes of 9 clinical isolates show that they are clonal, lack the virulence factors encoded by B. pertussis, and are more similar to nonpertussis bordetellae. New markers for B. holmesii can be developed using these sequences.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064020 | PMC |
| http://dx.doi.org/10.1128/genomeA.00438-14 | DOI Listing |
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