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Resonant Tunneling Nanostructures: Eliminating Current Saturation on Negative Differential Conductivity Region in Compact Dissipative Simulations.
Nanomaterials (Basel)
January 2025
Research Institute of Radio Electronics and Laser Technology of Bauman Moscow State Technical University, 105005 Moscow, Russia.
A solution to the problem of resonant tunneling current saturation is proposed. This problem does not allow, within the traditional compact models, a correct qualitative and quantitative analysis to be carried out of the volt-ampere characteristics of double-barrier heterostructures. The reason for this problem is the asymptotic behavior of the function describing the structure transparency, so a non-saturating compact model was proposed to solve the problem of current transfer analysis in the region of negative differential conductivity.
View Article and Find Full Text PDFEngineered ipilimumab variants that bind human and mouse CTLA-4.
MAbs
December 2025
Biotherapeutics and Genetic Medicine, AbbVie, South San Francisco, CA, USA.
Testing of candidate monoclonal antibody therapeutics in preclinical models is an essential step in drug development. Identification of antibody therapeutic candidates that bind their human targets and cross-react to mouse orthologs is often challenging, especially for targets with low sequence homology. In such cases, surrogate antibodies that bind mouse orthologs must be used.
View Article and Find Full Text PDFCellulose-based hydrogel simultaneously possessing solar and evaporative cooling performances for energy-saving window and personal thermal management.
Carbohydr Polym
March 2025
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China. Electronic address:
Thermochromic smart windows have been widely developed for building energy saving. However, most smart windows suffer from limited energy-saving performance, fixed phase transition temperature, and are not suitable for the temperature regulation needs of different application scenarios. Herein, a unique self-adaptive thermochromic hydrogel (HBPEC-PNA) with self-moisture-absorbing performance is reported that assembles solar energy cooling and evaporative heat dissipation.
View Article and Find Full Text PDFExceeding the limits of paediatric heat stress tolerance: the risk of losing a generation to climate inaction.
BMJ Paediatr Open
January 2025
Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA
Greenhouse gas (GHG) emissions are creating unprecedented climate-driven extreme weather, with levels of heat and humidity surpassing human physiological tolerance for heat stress. These conditions create a risk of mass casualties, with some populations particularly vulnerable due to physiological, behavioural and socioeconomic conditions (eg, lack of adequate shelter, limited healthcare infrastructure, sparse air conditioning access and electrical grid vulnerabilities). Children, especially young children, are uniquely vulnerable to extreme heat-related morbidity and mortality due to factors including low body mass, high metabolism, suboptimal thermoregulatory mechanisms and behavioural vulnerabilities.
View Article and Find Full Text PDFFemale athletes explicitly gesture in emotional situations.
Front Psychol
January 2025
Department of Motor Behavior in Sports, Institute of Health Promotion and Clinical Movement Science, German Sport University Cologne, Cologne, Germany.
Introduction: Both appraisal emotion approaches and self-regulation theory emphasize that appraising an event as conducive or detrimental to one's current goals may trigger an affective response that can be observed nonverbally. Because there may be a female advantage in the inhibition and self-regulation of emotions, we hypothesized that female but not male athletes regulate emotions during sports through explicit nonverbal behaviors.
Methods: All nonverbal hand movement behavior of right-handed female and male tennis athletes was recorded during competitive matches.
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