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The relationship between brain and visceral asymmetry: Evidence from situs inversus in humans.
Handb Clin Neurol
March 2025
Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium. Electronic address:
This review examines the relationship between visceral and brain asymmetry and explores whether their alignment observed in some vertebrate species also exists in humans. While the development of visceral and brain asymmetry may have occurred for different reasons, it is possible that the basic mechanisms for left-right differentiation of the visceral system were duplicated in the brain. We describe the main phenotypical anomalies and the general mechanism of left-right differentiation in vertebrates, followed by a systematic review of available human studies on behavioral and brain asymmetry in individuals with reversed visceral organization.
View Article and Find Full Text PDFLarge-scale genetic mapping for human brain asymmetry.
Handb Clin Neurol
March 2025
Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands; Department of Cognitive Neuroscience & Donders Community for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:
Left-right asymmetry is an important aspect of human brain organization for functions including language and hand motor control, which can be altered in some psychiatric traits. The last 5 years have seen rapid advances in the identification of specific genes linked to variation in asymmetry of the human brain and/or handedness. These advances have been driven by a new generation of large-scale genome-wide association studies, carried out in samples ranging from roughly 16,000 to over 1.
View Article and Find Full Text PDFLeft- and right-side unilateral spatial neglect: Hemispheric differences.
Handb Clin Neurol
March 2025
Department of Psychology, University of Milano-Bicocca, Milan, Italy; MiBTec, University of Milano-Bicocca, Milan, Italy. Electronic address:
Neglect of one side of space, typically contralateral to a lesion of one cerebral hemisphere, is a multicomponent neurologic syndrome. In humans, left neglect after right brain damage is more frequent, severe, or both, than right neglect after left brain damage. Right neglect is behaviorally like left neglect.
View Article and Find Full Text PDFCorrelation Between Facial Asymmetry and Maxillary Sinus Size or Volume Using Dental Cone-Beam Computed Tomography Images.
Cureus
March 2025
Department of Orthodontics, School of Dentistry, Kanagawa Dental University, Yokosuka, JPN.
Objectives This study investigated correlations between facial asymmetry and left-right differences in maxillary sinus size and volume, as well as their relationships with skeletal morphology. Methods The participants were 154 Japanese adults (56 men, 98 women) aged 18 to 38 years (mean age, 24.1 ± 5.
View Article and Find Full Text PDFThe left-right-handedness of the cylindrical spathe correlates with the phyllotactic spiral direction in Arisaema (Araceae).
Naturwissenschaften
February 2025
Botanical Gardens, Graduate School of Science, The University of Tokyo, Hakusan 3-7-1, Bunkyo-Ku, Tokyo, 112-0001, Japan.
A left-right asymmetry of plants has attracted attention in various study areas (e.g., developmental biology, ethology, and evolutionary biology); however, the underlying mechanisms remain unclear.
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