Largest pheochromocytoma reported in Canada: A case study and literature review.

Can Urol Assoc J

Urologist, Saskatoon Health Region, Saskatoon, SK.

Published: May 2014

Most giant pheochromocytomas do not present with classic symptoms, as documented by published case reports. Given this, clinicians have to consider a wide differential diagnosis for any retroperitoneal mass and perform screening tests to rule out a pheochromocytoma. We describe the largest pheochromocytoma reported in Canada, where the patient presented with a palpable abdominal mass and dyspnea. The 19 × 18 × 12-cm right retroperitoneal mass was biochemically active and was radiologically and pathologically consistent with a giant pheochromocytoma. We present this case and review the relevant current literature.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039607PMC
http://dx.doi.org/10.5489/cuaj.1719DOI Listing

Publication Analysis

Top Keywords

largest pheochromocytoma
8
pheochromocytoma reported
8
reported canada
8
retroperitoneal mass
8
canada case
4
case study
4
study literature
4
literature review
4
review giant
4
giant pheochromocytomas
4

Similar Publications

Paraganglioma and phaeochromocytoma in adult Fontan patients.

J Med Imaging Radiat Oncol

February 2025

Department of Medical Imaging, University Health Network, JDMI, Toronto, Ontario, Canada.

Introduction: The purpose of this study was to address the gap in knowledge in the incidence, presentation and imaging features of PPGL in Fontan patients. It has been hypothesised in the literature that Fontan circulation patients have an increased incidence of these tumours. This study is the largest cohort of adult Fontan patients in North America.

View Article and Find Full Text PDF

Medullary thyroid cancer (MTC) is a relatively rare thyroid malignancy, constituting a small percentage of all thyroid cancer cases. Even more rare is the occurrence of mixed MTC and papillary thyroid cancer (PTC), found in a very small fraction of MTC cases. These cancers originate from different cell types with distinct developmental origins.

View Article and Find Full Text PDF

Pheochromocytomas and paragangliomas are rare neuroendocrine tumours. Around 20-25 % of patients develop metastases, for which there is an urgent need of prognostic markers and therapeutic stratification strategies. The presence of a MAML3-fusion is associated with increased metastatic risk, but neither the processes underlying disease progression, nor targetable vulnerabilities have been addressed.

View Article and Find Full Text PDF

Robot-assisted laparoscopic adrenalectomy: Extended application in children.

Eur J Surg Oncol

December 2024

Department of Pediatric Surgery and Urology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France; Université de Paris Cité, Paris, France. Electronic address: https://twitter.com/hopital_necker.

Background: Minimally invasive surgery for paediatric adrenal tumours has evolved, but robot-assisted laparoscopic adrenalectomy (RALA) in children remains poorly studied. The current prospective study aims to demonstrate the safety and efficacy of RALA in treating children with adrenal tumours.

Methods: A prospective institutional analysis of children presenting with neuroblastic and endocrine tumours treated with RALA was undertaken over a six year-period.

View Article and Find Full Text PDF
Article Synopsis
  • This study examined the relationship between genetic variants and intraoperative haemodynamic instability (IHI) in patients undergoing surgery for pheochromocytomas and paragangliomas (PPGLs).
  • Out of 671 patients analyzed, 61.8% experienced IHI, with a significant correlation found between IHI and specific genetic mutations, particularly those in the HRAS gene.
  • Other factors influencing IHI included age at tumor diagnosis, presence of catecholamine-associated symptoms, and tumor size, with the genetic background being the most influential contributor.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!