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Assessing the factors militating against the effective implementation of electronic health records (EHR) in Nigeria.
Sci Rep
December 2024
Fidson Health Care PLC, Ibadan, Oyo State, Nigeria.
This study assessed the factors militating against the effective implementation of electronic health records (EHR) in Nigeria, the computerization of patients' health records with a lot of benefits including improved patients' satisfaction, improved care processes, reduction of patients' waiting time, and medication errors. Despite these benefits, healthcare organizations are slow to adopt the EHR system. Therefore, the study assessed the factors militating against the effective implementation of the EHR system, the level of awareness of EHR, and the utilization of electronic health records; it also investigated the factors militating against the effective implementation of EHR.
View Article and Find Full Text PDFTIMP-2 Promotes Wound Healing by Suppressing Matrix Metalloproteinases and Inflammatory Cytokines in Corneal Epithelial Cells.
Am J Pathol
December 2024
Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA. Electronic address:
Tissue inhibitors of metalloproteinases (TIMPs) modulate extracellular matrix (ECM) remodeling for maintaining homeostasis and promoting cell migration and proliferation. Pathological conditions can alter TIMP homeostasis and aggravate disease progression. The roles of TIMPs have been studied in tissue-related disorders; however, their contributions to tissue repair during corneal injury are undefined.
View Article and Find Full Text PDFA Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.
J Agric Food Chem
December 2024
Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Yuanmingyuan West Road, Beijing 100193, China.
In clinical mastitis of dairy cows, the abnormal accumulation of apoptotic cells (ACs) and subsequent secondary necrosis and inflammation pose significant concerns, with macrophage-mediated efferocytosis, crucial for ACs clearance, remaining unexplored in this context. In nonruminants, MER proto-oncogene tyrosine kinase (MERTK) receptors are essential for efferocytosis and A Disintegrin and Metalloproteinase 17 (ADAM17) is thought to play a role in regulating MERTK integrity. This study aimed to delineate the in situ role of efferocytosis in clinical mastitis, with a particular focus on the interaction between MERTK and ADAM17 in bovine macrophages.
View Article and Find Full Text PDFComparative analysis of heavy metals toxicity in drinking water of selected industrial zones in Gujranwala, Pakistan.
Sci Rep
December 2024
College of Water Conservancy and Architectural Engineering, Shihezi University, Shihezi, 832000, Xinjiang, China.
Heavy metal contamination of drinking water, primarily driven by industrial activities, represents a critical challenge, with implications for human health and environmental safety. Gujranwala is an industrial and thickly populated city. The current study aimed to assess and compare heavy metal contamination levels in drinking water from five industrial areas and evaluate their potential impacts on human health.
View Article and Find Full Text PDFMultifunctional nanocellulose hybrid films: From packaging to photovoltaics.
Int J Biol Macromol
December 2024
Physical Chemistry and Soft Matter, Wageningen University and Research, 6708 WE Wageningen, Netherlands. Electronic address:
This study aimed to develop eco-friendly multifunctional nanocellulose (NC) hybrid films with tailored properties for versatile applications including packaging and photovoltaics. Hybrid films composed by cellulose nanocrystals (CNC) and carboxymethylated cellulose nanofibrils (CNF) were produced at various mass ratio (CNC - 100:0 to 0:100). Montmorillonite clay (MTM) was incorporated (50 % by mass) into the CNC:CNF films.
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