Total skin electron irradiation (TSEI) for patients with cutaneous lymphomas is technically challenging, and numerous approaches have been developed to overcome the many field matching problems associated with such a large and complex treatment volume. Since 1981 we have delivered TSEI using a rotational total skin electron irradiation (RTSEI) technique in conjunction with patch, treat and boost fields in order to provide complete skin and dose coverage. Initially we used a 6 MeV electron beam at an extended source-skin distance (SSD) on a modified linear accelerator. More recently we began using a high dose rate electron mode on a commercially available linear accelerator. The RTSEI technique allows the delivery of a seamless surface dose to the majority of the patient's skin surface in a single treatment. In this review paper we present our three-decade experience with the technical development, dosimetry, treatment delivery and clinical outcomes of our RTSEI technique.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054995PMC
http://dx.doi.org/10.1016/j.rpor.2013.05.002DOI Listing

Publication Analysis

Top Keywords

total skin
12
skin electron
12
electron irradiation
12
rtsei technique
12
rotational total
8
irradiation rtsei
8
linear accelerator
8
skin
5
electron
5
institutional experience
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!