For decades, the standard method for screening and grading severity of diabetic retinal disease has relied upon a montage of photographs using normal angle fundus cameras. With the development of ultrawide field (UWF) fundus imaging, more of the retina can be imaged with fewer pictures, less dependence on photographer skill, and, often, greater ease on the patient. Recent studies have shown comparability between traditional and UWF imaging for standard grading of diabetic retinopathy. Moreover, UWF images can detect peripheral pathology not typically seen in standard photographs, which may enlighten our understanding of disease severity and suggest new indications for treatment.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s11892-014-0514-0 | DOI Listing |
Am J Ophthalmol
March 2025
Genentech, Inc., South San Francisco, CA.
Purpose: To investigate the safety, tolerability, and efficacy of intravitreal injection of galegenimab, an anti-HtrA1 FAb, in patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
Design: Phase 2, single-masked, randomized clinical trial.
Methods: Eligible GA patients with BCVA letter scores of ≥ 24 letters and baseline GA lesion size 2.
BMC Ophthalmol
March 2025
Department of Ophthalmology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Background: Acute retinal necrosis triggered by routine cataract surgery is a rare condition, which may be overlooked by the clinicians. We report a case of unilateral acute retinal necrosis (ARN) with the onset 4 days after uncomplicated cataract surgery. The patient demonstrates satisfactory outcomes following anti-virus therapy.
View Article and Find Full Text PDFOphthalmol Ther
March 2025
Department of Endocrinology and Metabolism, AIIMS, New Delhi, India.
Introduction: While many deep learning systems (DLSs) for diabetic retinopathy (DR) have been developed and validated on cohorts with an average age of 50s or older, fewer studies have examined younger individuals. This study aimed to understand DLS performance for younger individuals, who tend to display anatomic differences, such as prominent retinal sheen. This sheen can be mistaken for exudates or cotton wool spots, and potentially confound DLSs.
View Article and Find Full Text PDFOphthalmol Retina
March 2025
Moorfields Eye Hospital, London, United Kingdom; UCL Institute of Ophthalmology, University College London, London, United Kingdom. Electronic address:
Purpose: To analyze the retinal imaging findings and natural history of Best vitelliform macular dystrophy (BVMD).
Design: Single-center retrospective, consecutive, observational study.
Participants: Patients with a clinical diagnosis of BVMD, from pedigrees with a likely disease-causing monoallelic variant in BEST1.
J Fr Ophtalmol
March 2025
Department of Ophthalmology, University of Health Sciences, Basaksehir Cam and Sakura City Hospital, Basaksehir Olympic Boulevard Road, Basaksehir, Istanbul, Turkey.
Purpose: To evaluate the efficacy of navigated subthreshold micropulse laser (NSML) compared to subthreshold micropulse laser (SML) without navigation in the management of chronic central serous chorioretinopathy (CSCR).
Materials And Methods: This retrospective study included patients diagnosed with chronic CSCR who underwent either NSML or SML without navigation. Patients meeting inclusion criteria presented with serous macular detachment and leakage at the level of the retinal pigment epithelium on fundus fluorescein angiography (FFA).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!