Biosciences Division, Oak Ridge National Laboratory (ORNL), Oak Ridge, TN 37831, USA.
Published: October 2014
AI Article Synopsis
Article Abstract
A series of semiconducting zinc sulfide (ZnS) nanoparticles were scalably, reproducibly, controllably and economically synthesized with anaerobic metal-reducing Thermoanaerobacter species. These bacteria reduced partially oxidized sulfur sources to sulfides that extracellularly and thermodynamically incorporated with zinc ions to produce sparingly soluble ZnS nanoparticles with ∼5nm crystallites at yields of ∼5gl(-1)month(-1). A predominant sphalerite formation was facilitated by rapid precipitation kinetics, a low cation/anion ratio and a higher zinc concentration compared to background to produce a naturally occurring hexagonal form at the low temperature, and/or water adsorption in aqueous conditions. The sphalerite ZnS nanoparticles exhibited narrow size distribution, high emission intensity and few native defects. Scale-up and emission tunability using copper doping were confirmed spectroscopically. Surface characterization was determined using Fourier transform infrared and X-ray photoelectron spectroscopies, which confirmed amino acid as proteins and bacterial fermentation end products not only maintaining a nano-dimensional average crystallite size, but also increasing aggregation. The application of ZnS nanoparticle ink to a functional thin film was successfully tested for potential future applications.
Background: Ciprofloxacin is a widely used antibiotic in medicine and agriculture. It can cause pollution to the environment and food, thereby affecting human health.
Objective: This study proposes the preparation of molecular imprinted fluorescent sensors and their selective detection of ciprofloxacin, with the aim of achieving specific recognition and accurate detection of ciprofloxacin.
Excess intracellular HS induces destructive mitochondrial toxicity, while overload of Zn results in cell pyroptosis and potentiates the tumor immunogenicity for immunotherapy. However, the precise delivery of both therapeutics remains a great challenge. Herein, an electrically activable ZnS nanochip for the controlled release of HS and Zn was developed for enhanced gas-ionic-immunotherapy (GIIT).
- The study explored how different heat treatments affected the thermoluminescence (TL) and structure of zinc sulfide (ZnS) samples, revealing that annealing increased the proportion of the hexagonal wurtzite phase.
- The best thermoluminescence intensity was found in a sample with 8.2% wurtzite and 91.8% cubic zinc sulfide, with the analysis showing well-formed, aggregated ZnS nanoparticles.
- The researchers used advanced techniques to analyze TL glow curves, identifying multiple trapping energy peaks and determining activation energies related to electron traps in the samples.
Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing National Laboratory of Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University Nanjing Jiangsu 210023 China
Copper homeostasis is crucial for cells, especially for rapidly proliferating cancerous cells. Copper imbalance-induced cell death (, cuproptosis) has emerged as a new strategy for tumor therapy. While copper accumulation-induced cuproptosis has been extensively investigated and its underlying mechanism recently elaborated, copper depletion-induced cuproptosis remains largely unexplored.
The text discusses the importance of detecting non-steroidal anti-inflammatory drugs (NSAIDs) due to their common use and possible effects on health and the environment.
Recent advancements in sensing technologies for NSAIDs are explored, particularly focusing on molecular receptors using specialized fluorescent molecules and advanced nanostructured assemblies.
The review also addresses the binding mechanisms, challenges, and future directions in developing innovative sensors for rapid and selective NSAID detection, filling a gap in the existing literature on this topic.
