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Background: The use of carbon fiber or polyetheretherketone spine constructs has proven to be a safe and effective alternative to standard metal alloy. The mechanical properties of carbon fiber while unique provide a construct that is comparable in strength to previous titanium-based constructs and have additionally shown greater fatigue resistance. These constructs have been especially useful for the mechanical stabilization of the spine following tumor resection.
View Article and Find Full Text PDFCurrent and Emerging Therapies for Limbal Stem Cell Deficiency.
Stem Cells Transl Med
March 2022
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
The corneal epithelium serves to protect the underlying cornea from the external environment and is essential for corneal transparency and optimal visual function. Regeneration of this epithelium is dependent on a population of stem cells residing in the basal layer of the limbus, the junction between the cornea and the sclera. The limbus provides the limbal epithelial stem cells (LESCs) with an optimal microenvironment, the limbal niche, which strictly regulates their proliferation and differentiation.
View Article and Find Full Text PDFSepsis Among Medicare Beneficiaries: 4. Precoronavirus Disease 2019 Update January 2012-February 2020.
Crit Care Med
December 2021
United States Department of Health and Human Services, Center for Medicare and Medicaid Services, Baltimore, MD.
Objectives: To provide updated information on the burdens of sepsis during acute inpatient admissions for Medicare beneficiaries.
Design: Analysis of paid Medicare claims via the Centers for Medicare and Medicaid Services DataLink Project.
Setting: All U.
The association between vision impairment and social participation in community-dwelling adults: a systematic review.
Eye (Lond)
February 2020
Department of Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.
Vision impairment (VI) is an important contributor to the global burden of disability and is associated with decreased well-being. Recent research has attempted to devise a conceptual framework to explain the health consequences of VI. One proposed mechanism by which VI leads to declines in well-being and other adverse health and disability outcomes is through limitations in social participation (SP).
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