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Pediatric transplantation and tolerance: past, present, and future. | LitMetric

Pediatric transplantation and tolerance: past, present, and future.

Pediatr Transplant

Division of Organ Transplantation, Department of Surgery, Alpert Medical School of Brown University, Providence, RI, USA.

Published: August 2014

Solid organ transplantation is the treatment of choice in children with end-stage organ failure. With improving methods of transplant surgery and post-transplant care, transplantation is more frequently performed worldwide. However, lifelong and non-specific suppression of the recipient's immune system is a cause of significant morbidity in children, including infection, diabetes, and cancer. There is a great need to develop IS minimization/withdrawal and tolerance induction approaches.

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Source
http://dx.doi.org/10.1111/petr.12301DOI Listing

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