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Regulation of the IgE response by T follicular regulatory cells.
Allergol Int
January 2025
Department of Microbiology and Immunology, Indiana University School of Medicine, 950 W. Walnut St., R2 302 Indianapolis, IN 46202, USA. Electronic address:
Allergen-specific IgE is a major mediator of allergic responses and contributes greatly to allergic disease in the human population. Therapies that inhibit the production of IgE would be useful for lessening the burden of allergic disease. A great deal of research has focused on how IgE responses are regulated, and several factors that promote the production of allergic IgE have been characterized.
View Article and Find Full Text PDFFood-dependent exercise-induced anaphylaxis (FDEIA) suspected triggered by lipid transfer protein in a Chinese child: A case report.
Asia Pac Allergy
August 2024
Department of Allergy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Article Synopsis
- Lipid transfer protein (LTP) is a key protein linked to food-induced anaphylaxis, particularly in Mediterranean European countries, but this was the first reported case in China.
- A 12-year-old boy in China suffered from recurrent anaphylaxis triggered by intense exercise and showed high immunoglobulin E levels sensitized to various foods and pollens, especially mugwort and multiple grains and fruits.
- After receiving guidance on avoiding certain foods before exercise and carrying an epinephrine auto-injector, the boy experienced no further episodes over a 6-month follow-up, highlighting the need for awareness of LTP in similar cases.
Clinical and serological characteristics of patients allergic to LTP.
Allergol Immunopathol (Madr)
July 2024
Department of Public Health Sciences, University of Murcia School of Medicine, Murcia, Spain.
Background: Allergy to lipid transfer proteins (LPT) is common in Mediterranean Europe, and it causes severe reactions in patients and affects multiple foods, impairing the quality of life.
Objective: This study aimed to describe the clinical and sensitization profile of patients with LTP syndrome and to determine a clinical pattern of severity. Molecular diagnosis is shown in a broad population through microarrays.
Jug r 1 sensitization in 0- to 35-month-old children with egg, milk, or wheat sensitization.
J Allergy Clin Immunol Glob
November 2023
Aichi Children's Health and Medical Center, Allergy and Immunology Center, Obu, Japan.
Background: The incidence of tree nut allergies in children is increasing, with walnut allergy being the most common in the United States and Japan. Allergic reactions, including anaphylaxis, frequently occur at the first intake of tree nuts, suggesting prior sensitization.
Objective: Our aim was to identify which children should be considered for workup for preexisting sensitization.
Food allergy - New risks through vegan diet? Overview of new allergen sources and current data on the potential risk of anaphylaxis.
J Dtsch Dermatol Ges
November 2023
Department of Dermatology, Venereology and Allergology, University Hospital Leipzig, Germany.
A vegan diet is increasingly en vogue, i.e., a diet based on plants, in which animal products are completely avoided, often for health and environmental reasons.
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