Progressive outer retinal necrosis and immunosuppressive therapy in myasthenia gravis.

Case Rep Ophthalmol

Service d'Ophtalmologie, Centre Hospitalier Universitaire d'Angers, Université d'Angers, LUNAM, Angers, France ; Singapore National Eye Centre, Singapore Eye Research Institute and Duke-NUS, Singapore, Singapore.

Published: January 2014

Introduction: Progressive outer retinal necrosis (PORN) is a rare but devastating infectious retinitis associated with varicella zoster virus (VZV) and responsible for severe visual loss.

Case Report: A 59-year-old man treated for generalized myasthenia with oral azathioprine and prednisone presented with severe unilateral necrotizing retinitis. Polymerase chain reaction of the aqueous and vitreous humors was diagnostic for VZV PORN.

Conclusion: VZV PORN is a severe potential ocular complication of immunosuppression, prompting urgent diagnosis and appropriate treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036147PMC
http://dx.doi.org/10.1159/000362662DOI Listing

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