AI Article Synopsis
- - The study examined the effectiveness and safety of using ultrasound-guided methotrexate injections as a treatment for interstitial ectopic pregnancies in 14 patients where traditional surgical methods were not suitable.
- - All patients received a 25 mg injection of methotrexate directly into the gestational sac, successfully terminating the pregnancies without any complications during a year-long follow-up.
- - The findings suggest that this transabdominal approach is a viable and safe alternative for managing interstitial pregnancies when other methods are challenging, as long as appropriate patient selection and skilled operators are involved.
Article Abstract
Purpose: In a retrospective observational study, we evaluated the feasibility and safety of medical therapy with transabdominal ultrasound-guided injection of methotrexate (MTX) into the gestational sac (GS) in patients with interstitial ectopic pregnancies.
Methods: Fourteen interstitial ectopic pregnancies were treated with transabdominal ultrasound-guided injection of MTX (25 mg). All patients were hemodynamically stable. In all patients, the 10-cm distance between the GS and vaginal fornices was ≥10 cm, making transvaginal injection difficult. To evaluate feasibility and safety of the procedure, we assessed complications clinically and with imaging during a 1-year follow-up.
Results: In all 14 patients, MTX injected locally into the GS successfully terminated the interstitial pregnancy, thereby avoiding surgery. There was no complications during follow-up.
Conclusions: The successful outcome in our patients suggests that the transabdominal route is feasible and safe as a nonsurgical option for terminating an ectopic interstitial pregnancy in patients in whom the transvaginal route is contraindicated or difficult, provided the patients are properly selected and operators have sufficient experience with the technique.
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| http://dx.doi.org/10.1002/jcu.22185 | DOI Listing |
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