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Cardiovascular magnetic resonance-estimated pulmonary capillary wedge pressure, congestion markers, and effect of empagliflozin in patients with heart failure with reduced ejection fraction and dysglycaemia (SUGAR-DM-HF).
Eur J Heart Fail
January 2025
School of Cardiovascular and Metabolic Health, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Aims: A cardiovascular magnetic resonance (CMR) approach to non-invasively estimate left ventricular (LV) filling pressure was recently developed and shown to correlate with invasively measured pulmonary capillary wedge pressure (PCWP). We examined the association between CMR-estimated PCWP (CMR-PCWP) and other imaging and biomarker measures of congestion, and the effect of empagliflozin on these, in the SUGAR-DM-HF trial (NCT03485092).
Methods And Results: SUGAR-DM-HF enrolled 105 patients with heart failure with reduced ejection fraction (HFrEF) and pre-diabetes or type 2 diabetes who were randomly assigned to empagliflozin 10 mg or placebo once daily for 36 weeks.
Echocardiography-Guided Successful Off-Pump Submitral Aneurysm Repair With Coronary Artery Bypass.
Ann Thorac Surg Short Rep
December 2024
Department of Cardiothoracic Surgery, Government Medical College, Kottayam, Kerala, India.
Submitral aneurysm is a challenging and uncommon cardiac disease that is uniquely related to the posterior mitral valve leaflet. Awareness and prompt identification are vital because of the strong predilection for sudden fatal complications. Techniques and timing of surgical procedures are not standardized, especially in incidentally detected cases.
View Article and Find Full Text PDFAortopulmonary Window in Adult Patient Operated on With Echocardiography Assessment.
Ann Thorac Surg Short Rep
September 2024
Department of Pediatric Cardiac Intensive Care, Cardiac Center of Ethiopia and St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Adult aortopulmonary window is a rare presentation of a rare disease; only a few cases are reported to have undergone successful surgical closure without development of Eisenmenger syndrome. We describe the second oldest patient, a 25-year-old woman, who underwent successful surgical repair of aortopulmonary window after favorable indirect measures on echocardiography without the "gold standard" preoperative cardiac catheterization study. At 2 months after the operation, the patient remains in New York Heart Association class II.
View Article and Find Full Text PDFA computer vision model for the identification and scoring of calcium in aortic valve stenosis: a single-center experience.
Cardiovasc Diagn Ther
December 2024
East Slovak Institute of Cardiovascular Diseases and School of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia.
Background: Echocardiography is widely used to assess aortic stenosis (AS) but can yield inconsistent results, leading to uncertainty about AS severity and the need for further diagnostics. This retrospective study aimed to evaluate a novel echocardiography-based marker, the signal intensity coefficient (SIC), for its potential in accurately identifying and quantifying calcium in AS, enhancing noninvasive diagnostic methods.
Methods: Between May 2022 and October 2023, 112 cases of AS that were previously considered severe by echocardiography were retrospectively evaluated, as well as a group of 50 cases of mild or moderate AS, both at the Eastern Slovak Institute of Cardiovascular Diseases in Kosice, Slovakia.
Z-score evaluation and inferences for management of aortopathy patients.
Cardiol Young
January 2025
Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA.
Echocardiographic Z-score models play a crucial role in defining cardiac pathology in paediatric patients. There are multiple models that practitioners utilize in the United States without guiding principles to standardize their use. Discrepant interpretations can occur depending on the model chosen, even if standardized Z-score cutoffs are applied.
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