Surgery for neuroblastoma.

Prog Pediatr Surg

Hospital for Sick Children, London, UK.

Published: March 1989

Over a 33-month period, 31 infants and children had surgery for neuroblastoma. Twenty-three of the total had stage IV disease at the time of presentation and all but five had an abdominal primary tumour. In only two children was the tumour considered unresectable. The operative mortality was 3%. Neither ultrasound nor CT scanning could accurately predict resectability.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-642-72643-9_11DOI Listing

Publication Analysis

Top Keywords

surgery neuroblastoma
8
neuroblastoma 33-month
4
33-month period
4
period infants
4
infants children
4
children surgery
4
neuroblastoma twenty-three
4
twenty-three total
4
total stage
4
stage disease
4

Similar Publications

Donor-derived GD2-specific CAR T cells in relapsed or refractory neuroblastoma.

Nat Med

January 2025

Department of Hematology/Oncology, Cell and Gene Therapy, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Bambino Gesù Children's Hospital, Rome, Italy.

Allogeneic chimeric antigen receptor (CAR) T cells targeting disialoganglioside-GD2 (ALLO_GD2-CART01) could be a therapeutic option for patients with relapsed or refractory, high-risk neuroblastoma (r/r HR-NB) whose tumors did not respond to autologous GD2-CART01 or who have profound lymphopenia. We present a case series of five children with HR-NB refractory to more than three different lines of therapy who received ALLO_GD2-CART01 in a hospital exemption setting. Four of them had previously received allogeneic hematopoietic stem cell transplantation.

View Article and Find Full Text PDF

Background: Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy primarily treated with surgery. For tumors arising from the olfactory area, traditional treatment involves transcribriform resection of the anterior cranial fossa. Surgery can be performed with unilateral or bilateral resection depending on extent of involvement; however, there are currently no studies comparing outcomes between the two.

View Article and Find Full Text PDF

Retroperitoneal teratomas are rare neoplasms in neonates, presenting with nonspecific symptoms and variable clinical features, making diagnosis challenging. Radiological investigations, particularly fetal ultrasound and contrast-enhanced computed tomography, play a critical role in their detection. Differential diagnoses include neuroblastoma, adrenal hemorrhage, and congenital cystic lesions, which share overlapping clinical and imaging features.

View Article and Find Full Text PDF

Background And Objectives: Neuroblastoma, the most common extracranial solid tumor in children, is rare in adults. This study compares patient characteristics, disease patterns, and treatments among adults, adolescents, and children with neuroblastoma.

Methods: We queried the National Cancer Database (2004-2019) for neuroblastoma cases.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!