Purpose: reporting three rare cases of Marcus Gunn Syndrome and analyzing the clinical features of this entity.
Methods: Case reports of three patients with a Marcus Gunn Syndrome, treated at the Ophthalmology B CHU service Rabat - Morocco.
Results: Our patients are two boys aged 1 and 2 years old, and a 31 year old woman with a Marcus Gunn Syndrome. As special features, in the boys' cases this syndrome is bilateral, as for the other case it is associated with congenital fibrosis clinically predominant of the Ipsilateral inferior rectus muscle in an adult. Surgical treatment was not offered for children because of their young age. The adult patient has benefited from a recession of the inferior rectus muscle and a pleating in the superior rectus muscle. The forced duction test objectified a fibrosis of the inferior rectus muscle. Surgical correction of Ptosis and Synkinesis has not been indicated in this patient, given the residual oculomotor disorder and the risk of exposure keratitis.
Conclusion: Marcus Gunn Syndrome is exceptional in adults. This can be explained by the tendency of the lid retraction to fade with age. Bilateral involvement in Marcus Gunn Syndrome is rare. Its association with congenital fibrosis of extraocular muscles has allowed a better etiopathogenic approach highlighting a supra nuclear origin of this Syndrome.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Precarious employment, strenuous working conditions and the long-term risk of diagnosed chronic musculoskeletal disorders.
Occup Environ Med
December 2024
Unit of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden.
Objectives: To investigate the effect of precarious employment (PE) on the risk of diagnosed chronic musculoskeletal disorders (MSDs) among Swedish workers in occupations with strenuous working conditions.
Methods: This nationwide register-based cohort study included workers registered as living in Sweden in 2005, aged 21-60 at the 2010 baseline. Three samples were included: workers with high biomechanical workload (n=680 841), repetitive work (n=659 422) or low job control (n=703 645).
Progress in MGJWS: A 74-Year Review of Marcus Gunn Jaw-Winking Syndrome.
J Child Neurol
December 2024
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, No.639, Zhizaoju Road, Huangpu District, 200011, Shanghai, China.
Article Synopsis
- The text provides a detailed overview of Marcus Gunn jaw-winking syndrome, focusing on its epidemiology, and different possible diagnoses.
- It explores various causes and mechanisms behind the syndrome, including genetic factors and nerve abnormalities.
- Additionally, it reviews clinical symptoms, exceptional case presentations, and treatment options, both surgical and nonsurgical, for Marcus Gunn syndrome and related conditions.
Repeated dosing of AAV-mediated liver gene therapy in juvenile rat and mouse models of Crigler-Najjar syndrome type I.
Mol Ther Methods Clin Dev
December 2024
International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
Crigler-Najjar syndrome is an ultra-rare monogenic recessive liver disease caused by gene mutations. Complete UGT1A1 deficiency results in severe unconjugated hyperbilirubinemia in newborns that, if not treated, may lead to brain damage and death. Treatment is based on intensive phototherapy, but its efficacy decreases with age, rendering liver transplantation the only curative option.
View Article and Find Full Text PDFTrigemino-abducens synkinesis: serial review over 4 years.
J AAPOS
December 2024
Department of Ophthalmology, Gold Coast University Hospital, Gold Coast, Queensland; School of Medicine, Bond University, Gold Coast, Queensland, New Zealand.
Congenital cranial dysinnervation disorders involve abberant connections between cranial nerves, often resulting in synkinetic activation of target muscles. Marcus-Gunn jaw winking ptosis and Duane retraction syndrome are some of the more well-known examples of this phenomenon. We present serial video of a child with congenital trigemino-abducens synkinesis, a lesser known congenital cranial dysinnervation disorder, to demonstrate the characteristics of this likely under-diagnosed presentation.
View Article and Find Full Text PDFT1 erector spinae plane block for first rib resections in patients with thoracic outlet syndrome: a case series.
Proc (Bayl Univ Med Cent)
August 2024
Baylor University Medical Center, Dallas, Texas, USA.
An erector spinae plane block (ESPB), in which a local anesthetic is injected into the plane anterior to the erector spinae muscles, is a relatively new technique for delivering regional anesthesia and is typically performed in the mid-thoracic region. ESPBs demonstrate great potential to control regional neuropathic pain, and, accordingly, may be particularly effective at the T1 level for controlling pain in patients undergoing first rib resections for thoracic outlet syndrome (TOS). Four patients undergoing first rib resections for TOS were administered an ultrasound-guided ESPB at the T1 level.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!