Surface-initiated polymerization has been used to grow thick, uniform poly(methyl methacrylate) films on nanocantilever sensors. Cantilevers with these coatings yielded significantly greater sensitivity relative to bare devices as well as relative to devices that had been coated with drop-cast polymer films. The devices with surface-initiated polymer films also demonstrated high selectivity toward polar analytes. Surface-initiated polymerization can therefore provide a straightforward, reproducible method for large-scale functionalization of nanosensors.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297368 | PMC |
http://dx.doi.org/10.1021/nl500475b | DOI Listing |
Bioelectrochemistry
December 2024
Pharmacy College, Henan University of Chinese Medicine, Zhengzhou 450046, China; Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan Province, China. Electronic address:
Cardiac troponin I (cTnI) is known to be among the prominent diagnostic bio-marker for acute myocardial infarction (AMI). In this paper, we proposed an electrochemical aptasensor with nanomaterial MoS/CuS-Au as the substrate material and perillaldehyde (PA) as the surface-initiated reversible addition fragmentation chain transfer (SI-RAFT) polymerization monomer by mediating the in-situ deposition of silver metal on the electrode surface for ultrasensitive detection of cTnI. The substrate material MoS/CuS-Au not only accelerated the rate transfer between electron, but also provided more active sites for aptamers introduction.
View Article and Find Full Text PDFActa Biomater
December 2024
School of Chemistry and Pharmaceutical Engineering, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250021, China. Electronic address:
Postoperative adhesion (PA) caused by the combination of proteins, inflammatory response and bacterial infection poses substantial challenges for polypropylene meshes (PPMs) based hernioplasty. Herein, inspired by the peritoneum, a Janus PPMs with side-specific functions was developed via a surface-initiated photoiniferter-mediated polymerization technology. A physical barrier composed of zwitterionic polymer brushes (PS) was firstly constructed on the one side of the PPMs, while the polymethacrylic acid (PMAA) brushes acting as the linker for bioactive nanoparticles (HAP) were precisely situated on the opposite surface subsequently.
View Article and Find Full Text PDFBioelectrochemistry
November 2024
Life Science and Chemistry College, Hunan University of Technology, Zhuzhou 412007, China. Electronic address:
Early cancer diagnosis is paramount for enhancing treatment efficacy, extending patient survival, and improving the quality of life. We developed a highly sensitive electrochemical biosensor for the detection of target DNA (tDNA) associated with gastric cancer. This advancement integrates dual signal amplification strategies: bio-barcode amplification (BCA) and surface-initiated enzyme polymerization (SIEP), with copper nanoclusters (CuNCs) serving as signal labels.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Facultad de Química, Departamento de Ingeniería Química, Universidad Nacional Autónoma de México, 04510 Ciudad de México, Mexico. Electronic address:
The synthesis, characterization and evaluation of cellulose-graft-poly(4-vinylpirydine) for heavy metal removal from wastewater, is reported. Cellulose was obtained from a corn cob biomass using a recently developed gas-phase acid pretreatment process (GPAPP). The obtained corn cob cellulose (CCC) was functionalized by partial esterification of the superficial -OH groups with α-bromoisobutyryl bromide (BIBB) under mild conditions (room temperature and dimethyl formamide, DMF as solvent).
View Article and Find Full Text PDFChem Sci
November 2024
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University Lanzhou 730000 P. R. China
Herein, we present a straightforward CuBr-mediated surface-initiated controlled radical polymerization (SI-CRP) method for fabricating polymer brushes using microliter volumes of reaction solution in air and at room temperature. The key advantage of this method is its ability to rapidly grow polymer brushes with oxygen tolerance, driven by the controlled disproportionation of Cu into Cu and Cu by CuBr and ligand. We demonstrate the successful preparation of homo-, block, patterned, and wafer-scale polymer brushes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!