AI Article Synopsis
- A new and better method has been created for making methyl 1-fluoroindan-1-carboxylate (FICA Me ester) starting from 1-indanone.
- In addition, methyl 4-methyl-1-fluoroindan-1-carboxylate (4-Me-FICA Me ester) was made using the same improved method.
- This advancement in synthetic routes could enhance the efficiency of producing these chemical compounds.
Article Abstract
An improved synthetic route has been developed for the preparation of methyl 1-fluoroindan-1-carboxylate (FICA Me ester) from 1-indanone. Methyl 4-methyl-1-fluoroindan-1-carboxylate (4-Me-FICA Me ester) was also prepared following the same procedure.
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| http://dx.doi.org/10.1248/cpb.c14-00192 | DOI Listing |
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