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Automated craniofacial biometry with 3D T2w fetal MRI.
PLOS Digit Health
December 2024
Department of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas' Hospital, London, United Kingdom.
Objectives: Evaluating craniofacial phenotype-genotype correlations prenatally is increasingly important; however, it is subjective and challenging with 3D ultrasound. We developed an automated label propagation pipeline using 3D motion- corrected, slice-to-volume reconstructed (SVR) fetal MRI for craniofacial measurements.
Methods: A literature review and expert consensus identified 31 craniofacial biometrics for fetal MRI.
The Drivers and Barriers of Clinical Health Professions Student Flourishing: An Integrative Review.
J Physician Assist Educ
January 2025
Stephanie Neary, PhD, MPA, PA-C, is an assistant professor adjunct and the director of Didactic Education in the Yale University Physician Assistant Online Program, New Haven, Connecticut. This review was conducted while a PhD in Nursing Science student at the Medical University of South Carolina, Charleston, South Carolina.
Introduction: To determine the drivers and barriers to flourishing for clinical health professions students through a review of peer-reviewed literature.
Methods: Articles were analyzed in Scopus, PubMed, and EBSCOHost and hand-searched education journals through May 2024 describing flourishing among clinical health professions students. Whittemore and Knafl's integrative approach was used, and quality was assessed by the Mixed Methods Appraisal Tool.
Understanding co-production of injury research in Australian Aboriginal and Torres Strait Islander communities: a comprehensive scoping review.
Inj Epidemiol
January 2025
Jamieson Trauma Institute, Royal Brisbane and Women's Hospital, Metro North Health, L13, Block 7, Herston, Brisbane, QLD, 4029, Australia.
Background: Injury causes significant burden on Australian Aboriginal and Torres Strait Islander communities. However, a considerable portion of the research conducted in this area has been carried out by Western researchers. It has been acknowledged that historical research methodologies and discourses around Aboriginal and Torres Strait Islander research may not be suitable or beneficial.
View Article and Find Full Text PDFDurvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study.
J Immunother Cancer
January 2025
Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Background: The MOVIE phase I/II trial (NCT03518606) evaluated the safety and antitumor activity of durvalumab and tremelimumab combined with metronomic oral vinorelbine in patients with advanced tumors. We present the results of the recurrent advanced cervical cancer cohort.
Methods: Patients received tremelimumab (intravenously, 75 mg, every four weeks (Q4W); four cycles max) plus durvalumab (intravenously, 1,500 mg, Q4W; 26 cycles max) and metronomic oral vinorelbine (40 mg, every three weeks (3QW)) until disease progression.
Cynical Hostility, Intimacy and Relationship Satisfaction: The Role of Depressive Symptoms.
Behav Sci (Basel)
December 2024
School of Public Health, University of Haifa, Haifa 3498838, Israel.
Background: An individual's own and their perceived partner cynical hostility are conceptualized as vulnerability factors, decreasing couples' intimacy and relationship satisfaction. The perceived partner cynical hostility may be especially harmful when distress is high.
Method: Longitudinal data were collected in two waves (during and after the COVID-19 lockdown), relying on the respondents' self-reports.
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