We have developed a novel class of simple materials for sensing monosaccharides by the functionalization of graphene oxide (GO) with boronate-based fluorescence probes (BA1 and BA2). The composite materials were characterized by atomic force microscopy, Raman spectroscopy, and UV-vis/fluorescence spectroscopy. The strong fluorescence of the BA probes is quenched in the presence of GO through fluorescence resonance energy transfer. The BA@GO composite sensors formed provide a useful platform for fluorogenic detection of monosaccharides based on the strong affinity between the boronic acid receptor and monosaccharides. The BA@GO composite sensor displayed a "turn-on" fluorescence response with a good linear relationship toward fructose over a range of other saccharides.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/am500801g | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Expanding the recognition of monosaccharides and glycans: A comprehensive analytical approach using chemical-nose/tongue technology and a comparison to lectin microarrays.
BBA Adv
December 2024
Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8565, Japan.
Chemical-nose/tongue technologies are emerging as promising analytical tools for glycan analysis. After briefly introducing the importance of glycans and their analytical methods, including the lectin microarray (LMA) as one of the gold standards, the fundamental principles underlying chemical noses/tongues are explained and various applications for monosaccharides and glycans are introduced. Then, the similarities and differences of these two approaches are discussed.
View Article and Find Full Text PDFHigh glucose induces renal tubular epithelial cell senescence by inhibiting autophagic flux.
Hum Cell
January 2025
Department of Nephrology, Zhong Da Hospital, Gulou District, No. 87, Dingjiaqiao, Zhongyangmen Street, Nanjing, 210009, Jiangsu, China.
Autophagy, a cellular degradation process involving the formation and clearance of autophagosomes, is mediated by autophagic proteins, such as microtubule-associated protein 1 light chain 3 (LC3) and sequestosome 1 (p62), and modulated by 3-methyladenine (3-MA) as well as chloroquine (CQ). Senescence, characterised by permanent cell cycle arrest, is marked by proteins such as cyclin-dependent kinase inhibitor 1 (p21) and tumour protein 53 (p53). This study aims to investigate the relationship between cell senescence and renal function in diabetic kidney disease (DKD) and the effect of autophagy on high-glucose-induced cell senescence.
View Article and Find Full Text PDFFacet engineering of CuO for efficient electrochemical glucose sensing.
Anal Chim Acta
January 2025
Hubei Provincial Key Laboratory of Green Materials for Light Industry, School of Materials and Chemical Engineering, Hubei University of Technology, Wuhan, 430068, PR China. Electronic address:
Background: Accurate monitoring glucose level is significant for human health management, especially in the prevention, diagnosis, and management of diabetes. Electrochemical quantification of glucose is a convenient and rapid detection method, and the crucial aspect in achieving great sensing performance lies in the selection and design of the electrode material. Among them, CuO, with highly catalysis ability, is commonly used as electrocatalyst in non-enzymatic glucose sensing.
View Article and Find Full Text PDFPortable paper-based microfluidic devices with CuAgS NPs modification for multiplex intelligent visualized detection of adrenaline and glucose simultaneously.
Anal Chim Acta
January 2025
Center for Quantum Sciences and School of Physics, Northeast Normal University, Changchun, 130117, China.
Background: Adrenaline and glucose are essential biomarkers in human body for maintaining metabolic balance. Abnormal levels of adrenaline and glucose are associated with various diseases. Therefore, it is important to design portable, on-site devices for rapid adrenaline and glucose analysis to safeguard health.
View Article and Find Full Text PDFA highly stretchable, self-healing, self-adhesive polyacrylic acid/chitosan multifunctional composite hydrogel for flexible strain sensors.
Carbohydr Polym
March 2025
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 15 North Third Ring Road East, Chaoyang District, Beijing 100029, China. Electronic address:
Conductive hydrogels have emerged as excellent candidates for the design and construction of flexible wearable sensors and have attracted great attention in the field of wearable sensors. However, there are still serious challenges to integrating high stretchability, self-healing, self-adhesion, excellent sensing properties, and good biocompatibility into hydrogel wearable devices through easy and green strategies. In this paper, multifunctional conductive hydrogels (PCGB) with good biocompatibility, high tensile (1694 % strain), self-adhesive, and self-healing properties were fabricated by incorporating boric acid (BA) and glucose (Glu) simultaneously into polyacrylic acid (PAA) and chitosan (CS) polymer networks using a simple one-pot polymerization method.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!